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NASDAQ · RLAYBiotechnologyUpdated Nov 4, 2026

Relay Therapeutics, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Relay Therapeutics, Inc. (RLAY) is -40.25%

According to Relay Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -40.25%. This represents a change of 297.72% compared to the average of -10.12% of the last 4 quarters.

Relay Therapeutics, Inc. (RLAY) Historical ROE (quarterly & annually)

How has RLAY ROE performed in the past?

The mean historical ROE of Relay Therapeutics, Inc. over the last ten years is -16.85%. The current -40.25% ROE has changed 138.89% with respect to the historical average. Over the past ten years (40 quarters), RLAY's ROE was at its highest in in the December 2019 quarter at 13.25%. The ROE was at its lowest in in the June 2021 quarter at -31.27%.

Quarterly (TTM)
Annual

Average

-16.85%

Median

-35.55%

Minimum

-48.76%

Maximum

43.98%

Relay Therapeutics, Inc. (RLAY) ROE by Quarter and Year

Discovering the peaks and valleys of Relay Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 490.24%

Maximum Annual ROE = 43.98%

Minimum Annual Increase = -118.63%

Minimum Annual ROE = -48.76%

Quarterly (TTM)
Annual
YearROEChange
2025-48.76%12.29%
2024-43.42%-4.52%
2023-45.47%48.74%
2022-30.57%-24.57%
2021-40.53%490.24%
2020-6.87%-118.63%
201936.86%-16.19%

Relay Therapeutics, Inc. (RLAY) Average ROE

How has RLAY ROE performed in the past?

The current ROE of Relay Therapeutics, Inc. (RLAY) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-45.88%

5-year avg

-41.75%

10-year avg

-16.85%

Relay Therapeutics, Inc. (RLAY) ROE vs. Peers

How is RLAY’s ROE compared to its peers?

Relay Therapeutics, Inc.’s ROE is greater than Revolution Medicines, Inc. (-91.93%), greater than IDEAYA Biosciences, Inc. (-39.52%), greater than Tyra Biosciences, Inc. (-46.39%), greater than Erasca, Inc. (-80.43%), greater than Tango Therapeutics, Inc. (-25.74%), greater than Prelude Therapeutics Incorporated (-75.35%), greater than ORIC Pharmaceuticals, Inc. (-35.35%), greater than ArriVent BioPharma, Inc. (-50.26%), less than Nurix Therapeutics, Inc. (49.34%), greater than Kymera Therapeutics, Inc. (-22.39%),

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