Tyra Biosciences, Inc.

Tyra Biosciences, Inc. - ROEverified

TYRA

Price:

$28.32

Market Cap:

$1.68B

Tyra Biosciences, Inc. is a preclinical biopharmaceutical company focused on innovating treatments to tackle tumor resistance and enhance patient outcomes in oncology. Its flagship product candidate, TYRA-300, is a highly selective inhibitor of fibroblast growth factor receptor (FGFR)3, specifically engineered for the treatment of muscle-invasive bladder cancer. Beyond this, the company is advancing a pipeline of programs addressing other critical conditions, including FGFR2-related intrahepatic cholangiocarcinoma, FGFR3-associated achondroplasia, REarranged during transfection (RET) kinase aberrations, and various FGFR4-driven cancers. Tyra also leverages its proprietary SNAP platform, desi...[Read more]

Industry

Biotechnology

IPO Date

2021-09-15

Stock Exchange

NASDAQ

Ticker

TYRA

The ROE as of June 2026 (TTM) for Tyra Biosciences, Inc. (TYRA) is -42.66%

According to Tyra Biosciences, Inc.’s latest financial reports and current stock price. The company's current ROE is -42.66%. This represents a change of 295.49% compared to the average of -10.79% of the last 4 quarters.

Tyra Biosciences, Inc. (TYRA) Historical ROE (quarterly & annually)

How has TYRA ROE performed in the past?

The mean historical ROE of Tyra Biosciences, Inc. over the last ten years is 2.63%. The current -42.66% ROE has changed -1723.83% with respect to the historical average. Over the past ten years (40 quarters), TYRA's ROE was at its highest in in the December 2020 quarter at 27.02%. The ROE was at its lowest in in the December 2025 quarter at -13.05%.

Quarterly (TTM)
Annual

Average

2.63%

Median

-21.46%

Minimum

-46.28%

Maximum

85.59%

Tyra Biosciences, Inc. (TYRA) ROE by Quarter and Year

Discovering the peaks and valleys of Tyra Biosciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 146.24%

Maximum Annual ROE = 85.59%

Minimum Annual Increase = -112.76%

Minimum Annual ROE = -46.28%

Quarterly (TTM)
Annual
YearROEChange
2025-46.28%83.64%
2024-25.20%-25.54%
2023-33.85%57.73%
2022-21.46%146.24%
2021-8.71%-112.76%
202068.29%-20.21%

Tyra Biosciences, Inc. (TYRA) Average ROE

How has TYRA ROE performed in the past?

The current ROE of Tyra Biosciences, Inc. (TYRA) is greater than its 3-year, greater than its 5-year, and less than than its 10-year historical averages

3-year avg

-35.11%

5-year avg

-27.10%

10-year avg

2.63%

Tyra Biosciences, Inc. (TYRA) ROE vs. Peers

How is TYRA’s ROE compared to its peers?

Tyra Biosciences, Inc.’s ROE is greater than Rezolute, Inc. (-58.82%), greater than Savara Inc. (-87.19%), greater than Geron Corporation (-28.90%), greater than Prime Medicine, Inc. (-188.82%), greater than Day One Biopharmaceuticals, Inc. (-23.43%), greater than Kura Oncology, Inc. (-141.95%), greater than Maravai LifeSciences Holdings, Inc. (-44.72%), less than Nanobiotix S.A. (31.23%), less than ProKidney Corp. (7.40%), greater than EyePoint Pharmaceuticals, Inc. (-110.54%),

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