Prelude Therapeutics Incorporated

Prelude Therapeutics Incorporated - ROEverified

PRLD

Price:

$4.32

Market Cap:

$178.38M

Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on identifying and developing innovative, targeted cancer treatments for patient populations with unmet medical needs. Its pipeline includes PRT543, currently undergoing Phase 1 clinical evaluation for certain solid tumors and myeloid malignancies. Another asset, PRT811, is also in Phase 1 trials, targeting various solid tumors, notably glioblastoma multiforme. The company is additionally progressing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a powerful and highly kinome-selective CDK9 inhibitor; PRT-SCA2, which is in preclinical development for several genomically selecte...[Read more]

Industry

Biotechnology

IPO Date

2020-09-25

Stock Exchange

NASDAQ

Ticker

PRLD

The ROE as of June 2026 (TTM) for Prelude Therapeutics Incorporated (PRLD) is -118.24%

According to Prelude Therapeutics Incorporated’s latest financial reports and current stock price. The company's current ROE is -118.24%. This represents a change of 307.32% compared to the average of -29.03% of the last 4 quarters.

Prelude Therapeutics Incorporated (PRLD) Historical ROE (quarterly & annually)

How has PRLD ROE performed in the past?

The mean historical ROE of Prelude Therapeutics Incorporated over the last ten years is -37.20%. The current -118.24% ROE has changed 217.88% with respect to the historical average. Over the past ten years (40 quarters), PRLD's ROE was at its highest in in the December 2019 quarter at 20.32%. The ROE was at its lowest in in the June 2020 quarter at -42.14%.

Quarterly (TTM)
Annual

Average

-37.20%

Median

-45.23%

Minimum

-144.96%

Maximum

64.69%

Prelude Therapeutics Incorporated (PRLD) ROE by Quarter and Year

Discovering the peaks and valleys of Prelude Therapeutics Incorporated ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 88.26%

Maximum Annual ROE = 64.69%

Minimum Annual Increase = -148.09%

Minimum Annual ROE = -144.96%

Quarterly (TTM)
Annual
YearROEChange
2025-144.96%49.85%
2024-96.74%88.26%
2023-51.39%-13.00%
2022-59.07%51.19%
2021-39.07%45.61%
2020-26.83%-148.09%
201955.80%-13.75%

Prelude Therapeutics Incorporated (PRLD) Average ROE

How has PRLD ROE performed in the past?

The current ROE of Prelude Therapeutics Incorporated (PRLD) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-97.70%

5-year avg

-78.24%

10-year avg

-37.20%

Prelude Therapeutics Incorporated (PRLD) ROE vs. Peers

How is PRLD’s ROE compared to its peers?

Prelude Therapeutics Incorporated’s ROE is greater than Pyxis Oncology, Inc. (-135.60%), greater than Orchestra BioMed Holdings, Inc. (-137.99%), greater than Enanta Pharmaceuticals, Inc. (-64.04%), greater than Caribou Biosciences, Inc. (-100.13%), less than Inventiva S.A. (1.87%), greater than Tenaya Therapeutics, Inc. (-80.56%), greater than Avalo Therapeutics, Inc. (-97.55%), greater than Eupraxia Pharmaceuticals Inc. (-50.81%), less than Immuneering Corporation (-0.11%), less than Foghorn Therapeutics Inc. (85.78%),

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