Protagonist Therapeutics, Inc.

Protagonist Therapeutics, Inc.verified

PTGX

Price:

$87.33

Market Cap:

$5.46B

Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment ...[Read more]

Industry

Biotechnology

IPO Date

2016-08-11

Stock Exchange

NASDAQ

Ticker

PTGX

The Enterprise Value as of December 2025 (TTM) for Protagonist Therapeutics, Inc. (PTGX) is 5.36B

According to Protagonist Therapeutics, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 5.36B. This represents a change of 68.40% compared to the average of 3.18B of the last 4 quarters.

Protagonist Therapeutics, Inc. (PTGX) Historical Enterprise Value (quarterly & annually)

How has PTGX Enterprise Value performed in the past?

The mean historical Enterprise Value of Protagonist Therapeutics, Inc. over the last ten years is 655.11M. The current 5.36B Enterprise Value has changed 81.66% with respect to the historical average. Over the past ten years (40 quarters), PTGX's Enterprise Value was at its highest in in the September 2025 quarter at 4.13B. The Enterprise Value was at its lowest in in the March 2016 quarter at 40.22M.

Quarterly (TTM)
Annual

Average

655.11M

Median

337.49M

Minimum

64.80M

Maximum

2.29B

Protagonist Therapeutics, Inc. (PTGX) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Protagonist Therapeutics, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 249.45%

Maximum Annual Enterprise Value = 2.29B

Minimum Annual Increase = -73.94%

Minimum Annual Enterprise Value = 64.80M

Quarterly (TTM)
Annual
YearEnterprise ValueChange
20242.29B105.21%
20231.12B170.24%
2022412.96M-71.84%
20211.47B151.95%
2020582.03M249.45%
2019166.56M143.93%
201868.28M-73.94%
2017262.02M114.96%
2016121.89M88.11%
201564.80M8.85%

Protagonist Therapeutics, Inc. (PTGX) Average Enterprise Value

How has PTGX Enterprise Value performed in the past?

The current Enterprise Value of Protagonist Therapeutics, Inc. (PTGX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

1.27B

5-year avg

1.17B

10-year avg

655.11M

Protagonist Therapeutics, Inc. (PTGX) Enterprise Value vs. Peers

How is PTGX’s Enterprise Value compared to its peers?

Protagonist Therapeutics, Inc.’s Enterprise Value is greater than Arcellx, Inc. (3.78B), greater than Alkermes plc (4.29B), greater than TG Therapeutics, Inc. (5.11B), greater than Akero Therapeutics, Inc. (4.31B), greater than Kymera Therapeutics, Inc. (4.74B), greater than Immunovant, Inc. (3.49B), greater than Viking Therapeutics, Inc. (4.26B), greater than Crinetics Pharmaceuticals, Inc. (4.44B), less than PTC Therapeutics, Inc. (5.99B), greater than NewAmsterdam Pharma Company N.V. (3.52B),

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