The Enterprise Value as of December 2025 (TTM) for Spyre Therapeutics, Inc. (SYRE) is 1.96B

According to Spyre Therapeutics, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 1.96B. This represents a change of -7.71% compared to the average of 2.12B of the last 4 quarters.

Spyre Therapeutics, Inc. (SYRE) Historical Enterprise Value (quarterly & annually)

How has SYRE Enterprise Value performed in the past?

The mean historical Enterprise Value of Spyre Therapeutics, Inc. over the last ten years is 220.45M. The current 1.96B Enterprise Value has changed 88.77% with respect to the historical average. Over the past ten years (40 quarters), SYRE's Enterprise Value was at its highest in in the September 2025 quarter at 5.73B. The Enterprise Value was at its lowest in in the June 2023 quarter at -187908015.60.

Spyre Therapeutics, Inc. (SYRE) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Spyre Therapeutics, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Spyre Therapeutics, Inc. (SYRE) Average Enterprise Value

How has SYRE Enterprise Value performed in the past?

The current Enterprise Value of Spyre Therapeutics, Inc. (SYRE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Spyre Therapeutics, Inc. (SYRE) Enterprise Value vs. Peers

How is SYRE’s Enterprise Value compared to its peers?

Spyre Therapeutics, Inc.’s Enterprise Value is greater than Pharvaris N.V. (1.34B), greater than Immunome, Inc. (1.70B), greater than Wave Life Sciences Ltd. (1.07B), greater than Intellia Therapeutics, Inc. (925.20M), greater than Zymeworks Inc. (-43935349065.00), greater than Maze Therapeutics, Inc. (1.76B), greater than AbCellera Biologics Inc. (1.15B), greater than Upstream Bio, Inc. (1.46B), greater than Ardelyx, Inc. (1.58B), greater than Celldex Therapeutics, Inc. (1.95B),

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