The Enterprise Value as of December 2025 (TTM) for Upstream Bio, Inc. (UPB) is 1.46B

According to Upstream Bio, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 1.46B. This represents a change of 140.16% compared to the average of 605.89M of the last 4 quarters.

Upstream Bio, Inc. (UPB) Historical Enterprise Value (quarterly & annually)

How has UPB Enterprise Value performed in the past?

The mean historical Enterprise Value of Upstream Bio, Inc. over the last ten years is 691.83M. The current 1.46B Enterprise Value has changed 20.93% with respect to the historical average. Over the past ten years (40 quarters), UPB's Enterprise Value was at its highest in in the March 2024 quarter at 1.13B. The Enterprise Value was at its lowest in in the September 2023 quarter at 0.

Upstream Bio, Inc. (UPB) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Upstream Bio, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Upstream Bio, Inc. (UPB) Average Enterprise Value

How has UPB Enterprise Value performed in the past?

The current Enterprise Value of Upstream Bio, Inc. (UPB) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Upstream Bio, Inc. (UPB) Enterprise Value vs. Peers

How is UPB’s Enterprise Value compared to its peers?

Upstream Bio, Inc.’s Enterprise Value is less than Zenas BioPharma, Inc. (1.55B), greater than Intellia Therapeutics, Inc. (925.20M), greater than Wave Life Sciences Ltd. (1.07B), greater than Relay Therapeutics, Inc. (1.33B), greater than Pharvaris N.V. (1.34B), less than Syndax Pharmaceuticals, Inc. (1.94B), greater than Novavax, Inc. (1.10B), greater than Amylyx Pharmaceuticals, Inc. (985.24M), less than Terns Pharmaceuticals, Inc. (2.30B), less than Spyre Therapeutics, Inc. (1.96B),

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