The Enterprise Value as of April 2026 (TTM) for Upstream Bio, Inc. (UPB) is 399.81M

According to Upstream Bio, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 399.81M. This represents a change of -48.76% compared to the average of 780.24M of the last 4 quarters.

Upstream Bio, Inc. (UPB) Historical Enterprise Value (quarterly & annually)

How has UPB Enterprise Value performed in the past?

The mean historical Enterprise Value of Upstream Bio, Inc. over the last ten years is 859.32M. The current 399.81M Enterprise Value has changed 4.55% with respect to the historical average. Over the past ten years (40 quarters), UPB's Enterprise Value was at its highest in in the December 2025 quarter at 1.37B. The Enterprise Value was at its lowest in in the September 2023 quarter at 0.

Upstream Bio, Inc. (UPB) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Upstream Bio, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Upstream Bio, Inc. (UPB) Average Enterprise Value

How has UPB Enterprise Value performed in the past?

The current Enterprise Value of Upstream Bio, Inc. (UPB) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

Upstream Bio, Inc. (UPB) Enterprise Value vs. Peers

How is UPB’s Enterprise Value compared to its peers?

Upstream Bio, Inc.’s Enterprise Value is less than Zenas BioPharma, Inc. (752.80M), less than Intellia Therapeutics, Inc. (1.41B), less than Wave Life Sciences Ltd. (798.32M), less than Relay Therapeutics, Inc. (2.20B), less than Pharvaris N.V. (1.37B), less than Syndax Pharmaceuticals, Inc. (2.03B), less than Novavax, Inc. (1.31B), less than Amylyx Pharmaceuticals, Inc. (1.08B), less than Terns Pharmaceuticals, Inc. (4.24B), less than Spyre Therapeutics, Inc. (4.26B),

Build a custom stock screener for Upstream Bio, Inc. (UPB) and other stocks

One of the best ways to find valuable stocks to invest in is to build a custom made screener in your Excel or Google Sheets spreadsheet. This allows you to compare thousands of companies like Upstream Bio, Inc. using the financials and key metrics that matter to you in a single view.

The easiest way to set this up is to use the Wisesheets add-on and set your spreadsheet like this:

Covering all these metrics from financial, data, dividend data, key metrics and more you can get all the data you want for over 50+ exchanges worldwide.

Get your free trial here.

Upstream Bio, Inc. (UPB) and other stocks custom spreadsheet templates

The easiest way to analyze a company like Upstream Bio, Inc. or any others is to create a spreadsheet model that automatically retrieves all of the stock data you need.

Using Wisesheets you can set up a spreadsheet model like this with simple spreadsheet formulas. If you change the ticker you can get all of the data automatically updated for you.

Whether you need live data, historical price data, financials, dividend data, key metrics, analyst estimates, or anything else...Wisesheets has you covered.