Upstream Bio, Inc.

Upstream Bio, Inc.verified

UPB

Price:

$8.64

Market Cap:

$464.78M

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

Industry

Biotechnology

IPO Date

Stock Exchange

NASDAQ

Ticker

UPB

The PE Ratio as of May 2025 (TTM) for Upstream Bio, Inc. (UPB) is -5.17

According to Upstream Bio, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -5.17. This represents a change of -32.42% compared to the average of -7.65 of the last 4 quarters.

Upstream Bio, Inc. (UPB) Historical PE Ratio (quarterly & annually)

How has UPB PE Ratio performed in the past?

The mean historical PE Ratio of Upstream Bio, Inc. over the last ten years is -28.61. The current -5.17 PE Ratio has changed 1.71% with respect to the historical average. Over the past ten years (40 quarters), UPB's PE Ratio was at its highest in in the June 2024 quarter at 0. The PE Ratio was at its lowest in in the September 2023 quarter at -64.40.

Quarterly (TTM)
Annual

Average

-28.61

Median

-33.48

Minimum

-38.91

Maximum

-13.44

Upstream Bio, Inc. (UPB) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Upstream Bio, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 16.22%

Maximum Annual PE Ratio = -13.44

Minimum Annual Increase = -65.46%

Minimum Annual PE Ratio = -38.91

Quarterly (TTM)
Annual
YearPE RatioChange
2024-13.44-65.46%
2023-38.9116.22%

Upstream Bio, Inc. (UPB) Average PE Ratio

How has UPB PE Ratio performed in the past?

The current PE Ratio of Upstream Bio, Inc. (UPB) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-28.61

5-year avg

-28.61

10-year avg

-28.61

Upstream Bio, Inc. (UPB) PE Ratio vs. Peers

How is UPB’s PE Ratio compared to its peers?

Upstream Bio, Inc.’s PE Ratio is

CompanyPE RatioMarket cap

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