Protagonist Therapeutics, Inc.

Protagonist Therapeutics, Inc.verified




Market Cap:


Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment ...[Read more]



IPO Date


Stock Exchange




The PE Ratio as of May 2024 (TTM) for Protagonist Therapeutics, Inc. (PTGX) is 12.10

According to Protagonist Therapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is 12.10. This represents a change of -1898.94% compared to the average of -0.67 of the last 4 quarters.

Protagonist Therapeutics, Inc. (PTGX) Historical PE Ratio (quarterly & annually)

How has PTGX PE Ratio performed in the past?

The mean historical PE Ratio of Protagonist Therapeutics, Inc. over the last ten years is -7.51. The current 12.10 PE Ratio has changed -16209.32% with respect to the historical average. Over the past ten years (40 quarters), PTGX's PE Ratio was at its highest in in the December 2023 quarter at 12.66. The PE Ratio was at its lowest in in the December 2017 quarter at -34.41.

Quarterly (TTM)









Protagonist Therapeutics, Inc. (PTGX) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Protagonist Therapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 343.23%

Maximum Annual PE Ratio = -2.37

Minimum Annual Increase = -66.44%

Minimum Annual PE Ratio = -16.49

Quarterly (TTM)
YearPE RatioChange

Protagonist Therapeutics, Inc. (PTGX) Average PE Ratio

How has PTGX PE Ratio performed in the past?

The current PE Ratio of Protagonist Therapeutics, Inc. (PTGX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg


5-year avg


10-year avg


Protagonist Therapeutics, Inc. (PTGX) PE Ratio vs. Peers

How is PTGX’s PE Ratio compared to its peers?

Protagonist Therapeutics, Inc.’s PE Ratio is greater than Revolution Medicines, Inc. (-13.41), greater than Akero Therapeutics, Inc. (-6.59), greater than Avidity Biosciences, Inc. (-11.25), greater than Stoke Therapeutics, Inc. (-5.92), greater than Kura Oncology, Inc. (-11.07), greater than Merus N.V. (-17.04), greater than Replimune Group, Inc. (-1.99), greater than Cerevel Therapeutics Holdings, Inc. (-16.60), greater than Relay Therapeutics, Inc. (-2.64), greater than Pliant Therapeutics, Inc. (-5.38), greater than Black Diamond Therapeutics, Inc. (-3.16), greater than Arvinas, Inc. (-6.60), greater than Ventyx Biosciences, Inc. (-1.52), greater than IDEAYA Biosciences, Inc. (-23.60), greater than Verona Pharma plc (-16.52), greater than Syndax Pharmaceuticals, Inc. (-7.19), greater than Terns Pharmaceuticals, Inc. (-4.82), greater than X4 Pharmaceuticals, Inc. (-1.44), greater than Acumen Pharmaceuticals, Inc. (-3.90), greater than Day One Biopharmaceuticals, Inc. (-6.71), greater than HOOKIPA Pharma Inc. (-2.15),

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