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NASDAQ · IONSBiotechnologyUpdated Nov 2, 2026

Ionis Pharmaceuticals, Inc. enterprise value

Company valuation, historical trends, and peer comparisons.

The Enterprise Value as of November 2026 (TTM) for Ionis Pharmaceuticals, Inc. (IONS) is 9.01B

According to Ionis Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 9.01B. This represents a change of -35.82% compared to the average of 14.04B of the last 4 quarters.

Ionis Pharmaceuticals, Inc. (IONS) Historical Enterprise Value (quarterly & annually)

How has IONS Enterprise Value performed in the past?

The mean historical Enterprise Value of Ionis Pharmaceuticals, Inc. over the last ten years is 7.82B. The current 9.01B Enterprise Value has changed 15.30% with respect to the historical average. Over the past ten years (40 quarters), IONS's Enterprise Value was at its highest in in the June 2026 quarter at 15.18B. The Enterprise Value was at its lowest in in the December 2021 quarter at 4.67B.

Quarterly (TTM)
Annual

Average

7.82B

Median

7.11B

Minimum

4.67B

Maximum

14.90B

Ionis Pharmaceuticals, Inc. (IONS) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Ionis Pharmaceuticals, Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 132.75%

Maximum Annual Enterprise Value = 14.90B

Minimum Annual Increase = -44.40%

Minimum Annual Enterprise Value = 4.67B

Quarterly (TTM)
Annual
YearEnterprise ValueChange
202514.90B132.75%
20246.40B-22.77%
20238.29B28.50%
20226.45B38.03%
20214.67B-44.40%
20208.40B-1.65%
20198.55B13.70%
20187.52B12.13%
20176.70B6.95%
20166.27B-18.92%

Ionis Pharmaceuticals, Inc. (IONS) Average Enterprise Value

How has IONS Enterprise Value performed in the past?

The current Enterprise Value of Ionis Pharmaceuticals, Inc. (IONS) is less than than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

9.86B

5-year avg

8.14B

10-year avg

7.82B

Ionis Pharmaceuticals, Inc. (IONS) Enterprise Value vs. Peers

How is IONS’s Enterprise Value compared to its peers?

Ionis Pharmaceuticals, Inc.’s Enterprise Value is less than Alnylam Pharmaceuticals, Inc. (21.14B), less than Biogen Inc. (43.23B), greater than Ultragenyx Pharmaceutical Inc. (2.69B), less than BioMarin Pharmaceutical Inc. (14.57B), greater than PTC Therapeutics, Inc. (5.26B), greater than Sarepta Therapeutics, Inc. (2.39B), greater than Intellia Therapeutics, Inc. (1.60B), less than BridgeBio Pharma, Inc. (15.65B),

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Frequently asked questions❓

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What is the 3-year average Enterprise Value for Ionis Pharmaceuticals, Inc. (IONS)?

What is the 5-year average Enterprise Value for Ionis Pharmaceuticals, Inc. (IONS)?

How does the current Enterprise Value for Ionis Pharmaceuticals, Inc. (IONS) compare to its historical average?