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NASDAQ · DNLIBiotechnologyUpdated Nov 2, 2026

Denali Therapeutics Inc. enterprise value

Company valuation, historical trends, and peer comparisons.

The Enterprise Value as of November 2026 (TTM) for Denali Therapeutics Inc. (DNLI) is 2.80B

According to Denali Therapeutics Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 2.80B. This represents a change of -14.20% compared to the average of 3.27B of the last 4 quarters.

Denali Therapeutics Inc. (DNLI) Historical Enterprise Value (quarterly & annually)

How has DNLI Enterprise Value performed in the past?

The mean historical Enterprise Value of Denali Therapeutics Inc. over the last ten years is 2.96B. The current 2.80B Enterprise Value has changed -5.48% with respect to the historical average. Over the past ten years (40 quarters), DNLI's Enterprise Value was at its highest in in the December 2020 quarter at 9.63B. The Enterprise Value was at its lowest in in the September 2016 quarter at 0.

Quarterly (TTM)
Annual

Average

2.96B

Median

2.80B

Minimum

15.66M

Maximum

8.69B

Denali Therapeutics Inc. (DNLI) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of Denali Therapeutics Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 11.62%

Maximum Annual Enterprise Value = 8.69B

Minimum Annual Increase = -84.01%

Minimum Annual Enterprise Value = 15.66M

Quarterly (TTM)
Annual
YearEnterprise ValueChange
20252.73B-15.42%
20243.23B12.27%
20232.87B-13.81%
20223.33B-35.78%
20215.19B-40.27%
20208.69B423.91%
20191.66B-9.69%
20181.84B11.62%
201715.66M-84.01%
201697.96M190.27%

Denali Therapeutics Inc. (DNLI) Average Enterprise Value

How has DNLI Enterprise Value performed in the past?

The current Enterprise Value of Denali Therapeutics Inc. (DNLI) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

2.94B

5-year avg

3.47B

10-year avg

2.96B

Denali Therapeutics Inc. (DNLI) Enterprise Value vs. Peers

How is DNLI’s Enterprise Value compared to its peers?

Denali Therapeutics Inc.’s Enterprise Value is greater than Cognition Therapeutics, Inc. (34.20M), less than Ionis Pharmaceuticals, Inc. (9.12B), less than Amylyx Pharmaceuticals, Inc. (3.53B), greater than Neumora Therapeutics, Inc. Common Stock (-34759283.00), greater than ProMIS Neurosciences, Inc. (-24508470.00), greater than Rapport Therapeutics, Inc. Common Stock (1.16B), greater than Alector, Inc. (216.99M), less than Praxis Precision Medicines, Inc. (7.40B), less than Neurocrine Biosciences, Inc. (14.87B), greater than Biohaven Ltd. (2.57B),

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