Zymeworks Inc.

Zymeworks Inc.verified

ZYME

Price:

$22.88

Market Cap:

$1.68B

Zymeworks Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying, advancing, and bringing to market biological therapies aimed at combating cancer. Its pipeline features two primary experimental treatments: zanidatamab, a cutting-edge bispecific antibody currently undergoing Phase 1 and Phase 2 studies for various malignancies such as those affecting the biliary tract, gastroesophageal region (adenocarcinomas), breast, and colon; and ZW49, an antibody-drug conjugate targeting two sites on the human epidermal growth factor receptor 2 (HER2), which is in Phase 1 trials for advanced or spreading tumors that express HER2. Zymeworks maintains significant alli...[Read more]

Industry

Biotechnology

IPO Date

2017-04-28

Stock Exchange

NASDAQ

Ticker

ZYME

The ROE as of June 2026 (TTM) for Zymeworks Inc. (ZYME) is -37.79%

According to Zymeworks Inc.’s latest financial reports and current stock price. The company's current ROE is -37.79%. This represents a change of 216.38% compared to the average of -11.94% of the last 4 quarters.

Zymeworks Inc. (ZYME) Historical ROE (quarterly & annually)

How has ZYME ROE performed in the past?

The mean historical ROE of Zymeworks Inc. over the last ten years is -61.44%. The current -37.79% ROE has changed -38.49% with respect to the historical average. Over the past ten years (40 quarters), ZYME's ROE was at its highest in in the March 2017 quarter at 177.23%. The ROE was at its lowest in in the December 2016 quarter at -125.27%.

Quarterly (TTM)
Annual

Average

-61.44%

Median

-33.22%

Minimum

-375.57%

Maximum

25.22%

Zymeworks Inc. (ZYME) ROE by Quarter and Year

Discovering the peaks and valleys of Zymeworks Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 257.33%

Maximum Annual ROE = 25.22%

Minimum Annual Increase = -381.55%

Minimum Annual ROE = -375.57%

Quarterly (TTM)
Annual
YearROEChange
2025-30.22%-16.57%
2024-36.22%41.85%
2023-25.53%-201.22%
202225.22%-129.66%
2021-85.05%93.09%
2020-44.05%-25.60%
2019-59.20%-335.25%
201825.16%-381.55%
2017-8.94%-97.62%
2016-375.57%257.33%

Zymeworks Inc. (ZYME) Average ROE

How has ZYME ROE performed in the past?

The current ROE of Zymeworks Inc. (ZYME) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-30.66%

5-year avg

-30.36%

10-year avg

-61.44%

Zymeworks Inc. (ZYME) ROE vs. Peers

How is ZYME’s ROE compared to its peers?

Zymeworks Inc.’s ROE is greater than Maze Therapeutics, Inc. (-36.63%), greater than Ardelyx, Inc. (-38.11%), greater than Spyre Therapeutics, Inc. (-31.25%), greater than Pharvaris N.V. (-67.40%), greater than Intellia Therapeutics, Inc. (-57.27%), less than BioCryst Pharmaceuticals, Inc. (123.57%), greater than Immunome, Inc. (-51.15%), greater than Trevi Therapeutics, Inc. (-24.53%), greater than Wave Life Sciences Ltd. (-56.41%), greater than Upstream Bio, Inc. (-43.82%),

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