Zymeworks Inc.

Zymeworks Inc.verified

ZYME

Price:

$26.52

Market Cap:

$1.99B

Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, breast, and colorectal cancer; and ZW49, a biparatopic anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that is in Phase 1 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. The company has strategic partnerships with Merck Sharp & Dohme Research Ltd.; Eli Lilly and Company; Bristol-Myers S...[Read more]

Industry

Biotechnology

IPO Date

2017-04-28

Stock Exchange

NASDAQ

Ticker

ZYME

The ROE as of December 2025 (TTM) for Zymeworks Inc. (ZYME) is -24.48%

According to Zymeworks Inc.’s latest financial reports and current stock price. The company's current ROE is -24.48%. This represents a change of 406.33% compared to the average of -4.83% of the last 4 quarters.

Zymeworks Inc. (ZYME) Historical ROE (quarterly & annually)

How has ZYME ROE performed in the past?

The mean historical ROE of Zymeworks Inc. over the last ten years is -58.00%. The current -24.48% ROE has changed -57.80% with respect to the historical average. Over the past ten years (40 quarters), ZYME's ROE was at its highest in in the March 2017 quarter at 177.23%. The ROE was at its lowest in in the December 2016 quarter at -125.27%.

Quarterly (TTM)
Annual

Average

-58.00%

Median

-30.87%

Minimum

-375.57%

Maximum

50.03%

Zymeworks Inc. (ZYME) ROE by Quarter and Year

Discovering the peaks and valleys of Zymeworks Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 257.33%

Maximum Annual ROE = 50.03%

Minimum Annual Increase = -381.55%

Minimum Annual ROE = -375.57%

Quarterly (TTM)
Annual
YearROEChange
2024-36.22%41.85%
2023-25.53%-201.22%
202225.22%-129.66%
2021-85.05%93.09%
2020-44.05%-188.04%
201950.03%98.81%
201825.16%-381.55%
2017-8.94%-97.62%
2016-375.57%257.33%
2015-105.10%222.92%

Zymeworks Inc. (ZYME) Average ROE

How has ZYME ROE performed in the past?

The current ROE of Zymeworks Inc. (ZYME) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-12.18%

5-year avg

-33.12%

10-year avg

-58.00%

Zymeworks Inc. (ZYME) ROE vs. Peers

How is ZYME’s ROE compared to its peers?

Zymeworks Inc.’s ROE is greater than Maze Therapeutics, Inc. (-44.62%), greater than Ardelyx, Inc. (-36.91%), greater than Spyre Therapeutics, Inc. (-31.18%), greater than Pharvaris N.V. (-69.10%), greater than Intellia Therapeutics, Inc. (-57.24%), less than BioCryst Pharmaceuticals, Inc. (1.93%), greater than Immunome, Inc. (-87.36%), greater than Trevi Therapeutics, Inc. (-31.23%), greater than Wave Life Sciences Ltd. (-72.94%), greater than Upstream Bio, Inc. (-35.90%),

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