Zymeworks Inc.

Zymeworks Inc.verified

ZYME

Price:

$26.52

Market Cap:

$1.99B

Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, breast, and colorectal cancer; and ZW49, a biparatopic anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that is in Phase 1 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. The company has strategic partnerships with Merck Sharp & Dohme Research Ltd.; Eli Lilly and Company; Bristol-Myers S...[Read more]

Industry

Biotechnology

IPO Date

2017-04-28

Stock Exchange

NASDAQ

Ticker

ZYME

The PE Ratio as of December 2025 (TTM) for Zymeworks Inc. (ZYME) is -31.20

According to Zymeworks Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -31.20. This represents a change of -255.41% compared to the average of 20.08 of the last 4 quarters.

Zymeworks Inc. (ZYME) Historical PE Ratio (quarterly & annually)

How has ZYME PE Ratio performed in the past?

The mean historical PE Ratio of Zymeworks Inc. over the last ten years is -8.82. The current -31.20 PE Ratio has changed 35.26% with respect to the historical average. Over the past ten years (40 quarters), ZYME's PE Ratio was at its highest in in the June 2025 quarter at 102.02. The PE Ratio was at its lowest in in the March 2016 quarter at -23.77.

Quarterly (TTM)
Annual

Average

-8.82

Median

-10.35

Minimum

-15.51

Maximum

4.12

Zymeworks Inc. (ZYME) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Zymeworks Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 104.73%

Maximum Annual PE Ratio = 4.12

Minimum Annual Increase = -246.29%

Minimum Annual PE Ratio = -15.51

Quarterly (TTM)
Annual
YearPE RatioChange
2024-9.0550.11%
2023-6.03-246.29%
20224.12-202.18%
2021-4.03-69.42%
2020-13.1911.11%
2019-11.871.88%
2018-11.65-24.86%
2017-15.51104.73%
2016-7.57-43.70%
2015-13.45-32.49%

Zymeworks Inc. (ZYME) Average PE Ratio

How has ZYME PE Ratio performed in the past?

The current PE Ratio of Zymeworks Inc. (ZYME) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

-3.65

5-year avg

-5.64

10-year avg

-8.82

Zymeworks Inc. (ZYME) PE Ratio vs. Peers

How is ZYME’s PE Ratio compared to its peers?

Zymeworks Inc.’s PE Ratio is less than Maze Therapeutics, Inc. (-15.46), less than Ardelyx, Inc. (-25.33), greater than Spyre Therapeutics, Inc. (-77.84), less than Pharvaris N.V. (-7.72), less than Intellia Therapeutics, Inc. (-2.41), greater than BioCryst Pharmaceuticals, Inc. (-187.46), less than Immunome, Inc. (-8.23), greater than Trevi Therapeutics, Inc. (-42.62), less than Wave Life Sciences Ltd. (-10.48), less than Upstream Bio, Inc. (-14.28),

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