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NASDAQ · SPPIBiotechnologyUpdated Oct 25, 2026

Spectrum Pharmaceuticals, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of October 2026 (TTM) for Spectrum Pharmaceuticals, Inc. (SPPI) is -207.06%

According to Spectrum Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current ROE is -207.06%. This represents a change of 315.66% compared to the average of -49.81% of the last 4 quarters.

Spectrum Pharmaceuticals, Inc. (SPPI) Historical ROE (quarterly & annually)

How has SPPI ROE performed in the past?

The mean historical ROE of Spectrum Pharmaceuticals, Inc. over the last ten years is -97.32%. The current -207.06% ROE has changed 112.77% with respect to the historical average. Over the past ten years (40 quarters), SPPI's ROE was at its highest in in the June 2018 quarter at 3.99%. The ROE was at its lowest in in the June 2022 quarter at -86.85%.

Quarterly (TTM)
Annual

Average

-97.32%

Median

-35.70%

Minimum

-333.18%

Maximum

-17.96%

Spectrum Pharmaceuticals, Inc. (SPPI) ROE by Quarter and Year

Discovering the peaks and valleys of Spectrum Pharmaceuticals, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 161.14%

Maximum Annual ROE = -17.96%

Minimum Annual Increase = -166.48%

Minimum Annual ROE = -333.18%

Quarterly (TTM)
Annual
YearROEChange
2022-280.06%-15.94%
2021-333.18%161.14%
2020-127.58%79.42%
2019-71.11%67.84%
2018-42.37%63.13%
2017-25.97%-10.53%
2016-29.03%21.66%
2015-23.86%32.84%
2014-17.96%-18.60%
2013-22.06%-166.48%

Spectrum Pharmaceuticals, Inc. (SPPI) Average ROE

How has SPPI ROE performed in the past?

The current ROE of Spectrum Pharmaceuticals, Inc. (SPPI) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-246.94%

5-year avg

-170.86%

10-year avg

-97.32%

Spectrum Pharmaceuticals, Inc. (SPPI) ROE vs. Peers

How is SPPI’s ROE compared to its peers?

Spectrum Pharmaceuticals, Inc.’s ROE is greater than Alaunos Therapeutics, Inc. (-232.60%), greater than CARGO Therapeutics, Inc. Common Stock (-43.76%), greater than Vaccitech plc (-59.18%), greater than Theseus Pharmaceuticals, Inc. (-20.74%), greater than LakeShore Biopharma Co., Ltd (-18.43%), less than Zevra Therapeutics, Inc. (32.77%), greater than Acelyrin, Inc. (-44.54%), greater than LENZ Therapeutics, Inc. (-59.44%), less than Third Harmonic Bio, Inc. (16.41%), greater than Inozyme Pharma, Inc. (-102.90%),

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