Acelyrin, Inc.

Acelyrin, Inc.verified

SLRN

Price:

$2.27

Market Cap:

$229.17M

Acelyrin, Inc., a clinical biopharma company, focuses on identifying, acquiring, and accelerating the development and commercialization of transformative medicines. The company's lead product candidate is izokibep, a small protein therapeutic designed to inhibit IL-17A with high potency, which is in Phase 3 clinical trials for use in the treatment of Hidradenitis Suppurativa, Psoriatic Arthritis, and uveitis, as well as in Phase 2 clinical trials for use in the treatment of Axial Spondyloarthritis. It is also developing lonigutamab, a humanized immunoglobulin G1 (IgG1) monoclonal antibody against insulin-like growth factor 1 receptor, which is in Phase 1 clinical trials for use in the treatm...[Read more]

Industry

Biotechnology

IPO Date

2023-05-04

Stock Exchange

NASDAQ

Ticker

SLRN

The ROE as of November 2025 (TTM) for Acelyrin, Inc. (SLRN) is -54.74%

According to Acelyrin, Inc.’s latest financial reports and current stock price. The company's current ROE is -54.74%. This represents a change of 297.53% compared to the average of -13.77% of the last 4 quarters.

Acelyrin, Inc. (SLRN) Historical ROE (quarterly & annually)

How has SLRN ROE performed in the past?

The mean historical ROE of Acelyrin, Inc. over the last ten years is -24.52%. The current -54.74% ROE has changed 123.22% with respect to the historical average. Over the past ten years (40 quarters), SLRN's ROE was at its highest in in the December 2022 quarter at 184.48%. The ROE was at its lowest in in the March 2022 quarter at -17.76%.

Quarterly (TTM)
Annual

Average

-24.52%

Median

-56.16%

Minimum

-85.27%

Maximum

99.48%

Acelyrin, Inc. (SLRN) ROE by Quarter and Year

Discovering the peaks and valleys of Acelyrin, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 99.48%

Minimum Annual Increase = -185.71%

Minimum Annual ROE = -85.27%

Quarterly (TTM)
Annual
YearROEChange
2024-54.16%-6.85%
2023-58.15%-31.81%
2022-85.27%-185.71%

Acelyrin, Inc. (SLRN) Average ROE

How has SLRN ROE performed in the past?

The current ROE of Acelyrin, Inc. (SLRN) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-65.86%

5-year avg

-24.52%

10-year avg

-24.52%

Acelyrin, Inc. (SLRN) ROE vs. Peers

How is SLRN’s ROE compared to its peers?

Acelyrin, Inc.’s ROE is greater than CARGO Therapeutics, Inc. Common Stock (-69.24%), greater than Inhibrx Biosciences, Inc. (-186.06%), greater than Cytocom, Inc. (-160.02%), greater than Alaunos Therapeutics, Inc. (-167.97%), greater than Catabasis Pharmaceuticals, Inc. (-24.29%), greater than Third Harmonic Bio, Inc. (-19.27%), greater than Spectrum Pharmaceuticals, Inc. (-207.06%), greater than Merrimack Pharmaceuticals, Inc. (-6.22%), less than Celularity Inc. (763.31%), greater than Inozyme Pharma, Inc. (-159.97%),

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