Scilex Holding Company

Scilex Holding Companyverified

SCLX

Price:

$8.5

Market Cap:

$72.18M

Scilex Holding Company is a biopharmaceutical enterprise that specializes in the development and market introduction of non-opioid therapies designed to alleviate both acute and chronic pain. Its primary marketed offering is ZTlido 1.8%, a topical prescription formulation of lidocaine specifically engineered to mitigate neuropathic discomfort associated with post-herpetic neuralgia, a condition characterized by persistent nerve pain following shingles. Beyond this, the company's development pipeline includes SP-102, a viscous gel corticosteroid for epidural administration, currently undergoing Phase III trials for lumbosacral radicular pain. Another candidate, SP-103, is progressing through ...[Read more]

Industry

Drug Manufacturers - General

IPO Date

2021-03-05

Stock Exchange

NASDAQ

Ticker

SCLX

The ROE as of June 2026 (TTM) for Scilex Holding Company (SCLX) is 190.13%

According to Scilex Holding Company’s latest financial reports and current stock price. The company's current ROE is 190.13%. This represents a change of 256.64% compared to the average of 53.31% of the last 4 quarters.

Scilex Holding Company (SCLX) Historical ROE (quarterly & annually)

How has SCLX ROE performed in the past?

The mean historical ROE of Scilex Holding Company over the last ten years is 40.73%. The current 190.13% ROE has changed 366.79% with respect to the historical average. Over the past ten years (40 quarters), SCLX's ROE was at its highest in in the September 2025 quarter at 145.38%. The ROE was at its lowest in in the March 2023 quarter at -277.65%.

Quarterly (TTM)
Annual

Average

40.73%

Median

37.79%

Minimum

-64.47%

Maximum

172.65%

Scilex Holding Company (SCLX) ROE by Quarter and Year

Discovering the peaks and valleys of Scilex Holding Company ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = Infinity%

Maximum Annual ROE = 172.65%

Minimum Annual Increase = -263.23%

Minimum Annual ROE = -64.47%

Quarterly (TTM)
Annual
YearROEChange
2025172.65%356.82%
202437.79%-42.83%
202366.11%-202.54%
2022-64.47%-263.23%
202139.50%17.76%
202033.54%Infinity%

Scilex Holding Company (SCLX) Average ROE

How has SCLX ROE performed in the past?

The current ROE of Scilex Holding Company (SCLX) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

92.19%

5-year avg

50.32%

10-year avg

40.73%

Scilex Holding Company (SCLX) ROE vs. Peers

How is SCLX’s ROE compared to its peers?

Scilex Holding Company’s ROE is less than Opus Genetics, Inc. (6.07%), greater than Acumen Pharmaceuticals, Inc. (-123.07%), greater than Citius Oncology, Inc. (-99.47%), greater than Inovio Pharmaceuticals, Inc. (-666.47%), greater than Incannex Healthcare Limited (-122.57%), greater than Seer, Inc. (-26.58%), greater than Agenus Inc. (-23.05%), greater than Lucid Diagnostics Inc. (-370.21%), greater than VistaGen Therapeutics, Inc. (-109.73%), greater than Alector, Inc. (-295.17%),

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