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NASDAQ · VTGNBiotechnologyUpdated Nov 4, 2026

VistaGen Therapeutics, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for VistaGen Therapeutics, Inc. (VTGN) is -152.59%

According to VistaGen Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -152.59%. This represents a change of 268.96% compared to the average of -41.36% of the last 4 quarters.

VistaGen Therapeutics, Inc. (VTGN) Historical ROE (quarterly & annually)

How has VTGN ROE performed in the past?

The mean historical ROE of VistaGen Therapeutics, Inc. over the last ten years is -273.65%. The current -152.59% ROE has changed -44.24% with respect to the historical average. Over the past ten years (40 quarters), VTGN's ROE was at its highest in in the June 2020 quarter at 61.70%. The ROE was at its lowest in in the December 2018 quarter at -426.32%.

Quarterly (TTM)
Annual

Average

-273.65%

Median

-134.99%

Minimum

-1665.39%

Maximum

362.59%

VistaGen Therapeutics, Inc. (VTGN) ROE by Quarter and Year

Discovering the peaks and valleys of VistaGen Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 564.55%

Maximum Annual ROE = 362.59%

Minimum Annual Increase = -205.00%

Minimum Annual ROE = -1665.39%

Quarterly (TTM)
Annual
YearROEChange
2026-196.19%168.57%
2025-73.05%184.32%
2024-25.69%-94.76%
2023-490.46%564.55%
2022-73.80%278.52%
2021-19.50%-105.38%
2020362.59%-204.33%
2019-347.55%67.56%
2018-207.41%-87.55%
2017-1665.39%-205.00%

VistaGen Therapeutics, Inc. (VTGN) Average ROE

How has VTGN ROE performed in the past?

The current ROE of VistaGen Therapeutics, Inc. (VTGN) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-98.31%

5-year avg

-171.84%

10-year avg

-273.65%

VistaGen Therapeutics, Inc. (VTGN) ROE vs. Peers

How is VTGN’s ROE compared to its peers?

VistaGen Therapeutics, Inc.’s ROE is less than Spero Therapeutics, Inc. (16.17%), greater than Seer, Inc. (-27.23%), greater than Seres Therapeutics, Inc. (-148.34%), less than Opus Genetics, Inc. (1.15%), greater than Cognition Therapeutics, Inc. (-50.17%), greater than TuHURA Biosciences, Inc. (-154.32%), greater than Agenus Inc. (-38.12%), greater than Actuate Therapeutics Inc (-346.18%), greater than Acumen Pharmaceuticals, Inc. (-166.49%), greater than Inovio Pharmaceuticals, Inc. (-1005.80%),

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