Phio Pharmaceuticals Corp.

Phio Pharmaceuticals Corp. - ROEverified

PHIO

Price:

$1.07

Market Cap:

$12.43M

Phio Pharmaceuticals Corp., a clinical stage biopharmaceutical company, engages in the development of immuno-oncology therapeutics in the United States. It develops PH-762, an INTASYL compound designed to reduce the expression of PD-1 in multi-center Phase 1b dose-escalating clinical trials; PH-894, an INTASYL compound that is designed to specifically silence BRD4, a protein that controls gene expression in both T cells and tumor cells in preclinical studies. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio Pharmaceuticals Corp. was founded in 2003 and is based in King Of Prussia, Pennsylvania.

Industry

Biotechnology

IPO Date

2012-05-10

Stock Exchange

NASDAQ

Ticker

PHIO

The ROE as of August 2026 (TTM) for Phio Pharmaceuticals Corp. (PHIO) is -77.34%

According to Phio Pharmaceuticals Corp.’s latest financial reports and current stock price. The company's current ROE is -77.34%. This represents a change of 277.93% compared to the average of -20.46% of the last 4 quarters.

Phio Pharmaceuticals Corp. (PHIO) Historical ROE (quarterly & annually)

How has PHIO ROE performed in the past?

The mean historical ROE of Phio Pharmaceuticals Corp. over the last ten years is -154.00%. The current -77.34% ROE has changed -49.78% with respect to the historical average. Over the past ten years (40 quarters), PHIO's ROE was at its highest in in the June 2021 quarter at -9.32%. The ROE was at its lowest in in the March 2018 quarter at -394.89%.

Quarterly (TTM)
Annual

Average

-154.00%

Median

-94.38%

Minimum

-679.32%

Maximum

-43.17%

Phio Pharmaceuticals Corp. (PHIO) ROE by Quarter and Year

Discovering the peaks and valleys of Phio Pharmaceuticals Corp. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 719.89%

Maximum Annual ROE = -43.17%

Minimum Annual Increase = -92.02%

Minimum Annual ROE = -679.32%

Quarterly (TTM)
Annual
YearROEChange
2025-43.17%-71.48%
2024-151.39%8.09%
2023-140.05%32.24%
2022-105.90%74.81%
2021-60.58%-10.32%
2020-67.56%-56.41%
2019-154.98%185.90%
2018-54.21%-92.02%
2017-679.32%719.89%
2016-82.86%-27.95%

Phio Pharmaceuticals Corp. (PHIO) Average ROE

How has PHIO ROE performed in the past?

The current ROE of Phio Pharmaceuticals Corp. (PHIO) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-111.54%

5-year avg

-100.22%

10-year avg

-154.00%

Phio Pharmaceuticals Corp. (PHIO) ROE vs. Peers

How is PHIO’s ROE compared to its peers?

Phio Pharmaceuticals Corp.’s ROE is greater than TransCode Therapeutics, Inc. (-99.39%), greater than Kiora Pharmaceuticals, Inc. (-59.30%), greater than IN8bio, Inc. (-96.39%), greater than BioCardia, Inc. (-5456.14%), greater than Aprea Therapeutics, Inc. (-59.54%), greater than Marker Therapeutics, Inc. (-73.29%), greater than Damora Therapeutics, Inc. (-122.61%), greater than Creative Medical Technology Holdings, Inc. (-88.50%), greater than Acurx Pharmaceuticals, Inc. (-153.93%), greater than Aptevo Therapeutics Inc. (-198.50%),

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