Aprea Therapeutics, Inc.

Aprea Therapeutics, Inc.verified

APRE

Price:

$1.06

Market Cap:

$6.47M

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel cancer therapeutics that target DNA damage response pathways. Its lead product candidate is ATRN-119, an oral ATR inhibitor that is in phase 1/2a clinical trial to treat patients with advanced solid tumors. The company's products pipeline also includes ATRN-Backup, an ATR inhibitor; ATRN-W1051 to treat anti-tumor activity; and ATRN-DDRi. Aprea Therapeutics, Inc. is based in Boston, Massachusetts.

Industry

Biotechnology

IPO Date

2019-10-03

Stock Exchange

NASDAQ

Ticker

APRE

The ROE as of December 2025 (TTM) for Aprea Therapeutics, Inc. (APRE) is -75.30%

According to Aprea Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -75.30%. This represents a change of 283.71% compared to the average of -19.63% of the last 4 quarters.

Aprea Therapeutics, Inc. (APRE) Historical ROE (quarterly & annually)

How has APRE ROE performed in the past?

The mean historical ROE of Aprea Therapeutics, Inc. over the last ten years is -139.29%. The current -75.30% ROE has changed -45.94% with respect to the historical average. Over the past ten years (40 quarters), APRE's ROE was at its highest in in the June 2022 quarter at 274.78%. The ROE was at its lowest in in the December 2022 quarter at -432.00%.

Quarterly (TTM)
Annual

Average

-139.29%

Median

-68.39%

Minimum

-876.92%

Maximum

42.47%

Aprea Therapeutics, Inc. (APRE) ROE by Quarter and Year

Discovering the peaks and valleys of Aprea Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 1.09%

Maximum Annual ROE = 42.47%

Minimum Annual Increase = -170.40%

Minimum Annual ROE = -876.92%

Quarterly (TTM)
Annual
YearROEChange
2024-67.12%-14.20%
2023-78.22%-91.08%
2022-876.92%1.09%
2021-73.80%5.94%
2020-69.66%227.79%
2019-21.25%-170.40%
201830.19%-28.92%

Aprea Therapeutics, Inc. (APRE) Average ROE

How has APRE ROE performed in the past?

The current ROE of Aprea Therapeutics, Inc. (APRE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-340.75%

5-year avg

-233.15%

10-year avg

-139.29%

Aprea Therapeutics, Inc. (APRE) ROE vs. Peers

How is APRE’s ROE compared to its peers?

Aprea Therapeutics, Inc.’s ROE is greater than Acurx Pharmaceuticals, Inc. (-219.56%), greater than BioCardia, Inc. (-58896.55%), greater than Kiora Pharmaceuticals, Inc. (-47.17%), greater than Galecto, Inc. (-130.67%), greater than Adial Pharmaceuticals, Inc. (-197.71%), greater than IN8bio, Inc. (-145.52%), greater than Creative Medical Technology Holdings, Inc. (-83.00%), less than HCW Biologics Inc. (507.82%), greater than Aptevo Therapeutics Inc. (-675.52%), greater than TransCode Therapeutics, Inc. (-1354.71%),

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