Orchard Therapeutics plc

Orchard Therapeutics plcverified

ORTX

Price:

$16.7

Market Cap:

$380.11M

Orchard Therapeutics plc, a biopharmaceutical company, develops gene therapies for serious and life-threatening rare diseases in the United Kingdom, European Union, and the United States. The company's gene therapy approach seeks to transform a patient's hematopoietic stem cells into a gene-modified cellular drug product to treat the patient's disease through a single administration. It provides Strimvelis, a gammaretroviral-based product for the treatment of adenosine deaminase-severe combined immunodeficiency (ADA-SCID). The company's clinical development products comprise OTL-101 for the treatment of ADA-SCID; OTL-200 to treat metachromatic leukodystrophy; OTL-103 for the treatment of Wis...[Read more]

Industry

Biotechnology

IPO Date

2018-10-31

Stock Exchange

NASDAQ

Ticker

ORTX

The ROE as of November 2025 (TTM) for Orchard Therapeutics plc (ORTX) is -5.12%

According to Orchard Therapeutics plc’s latest financial reports and current stock price. The company's current ROE is -5.12%. This represents a change of -131.55% compared to the average of 16.21% of the last 4 quarters.

Orchard Therapeutics plc (ORTX) Historical ROE (quarterly & annually)

How has ORTX ROE performed in the past?

The mean historical ROE of Orchard Therapeutics plc over the last ten years is -24.24%. The current -5.12% ROE has changed -78.90% with respect to the historical average. Over the past ten years (40 quarters), ORTX's ROE was at its highest in in the December 2022 quarter at 137.28%. The ROE was at its lowest in in the June 2018 quarter at -1059.49%.

Quarterly (TTM)
Annual

Average

-24.24%

Median

-46.00%

Minimum

-85.17%

Maximum

115.50%

Orchard Therapeutics plc (ORTX) ROE by Quarter and Year

Discovering the peaks and valleys of Orchard Therapeutics plc ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 60.95%

Maximum Annual ROE = 115.50%

Minimum Annual Increase = -139.82%

Minimum Annual ROE = -85.17%

Quarterly (TTM)
Annual
YearROEChange
2022-8.02%-53.66%
2021-17.31%-79.67%
2020-85.17%55.94%
2019-54.62%-26.22%
2018-74.03%60.95%
2017-46.00%-139.82%

Orchard Therapeutics plc (ORTX) Average ROE

How has ORTX ROE performed in the past?

The current ROE of Orchard Therapeutics plc (ORTX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-36.84%

5-year avg

-47.83%

10-year avg

-24.24%

Orchard Therapeutics plc (ORTX) ROE vs. Peers

How is ORTX’s ROE compared to its peers?

Orchard Therapeutics plc’s ROE is greater than Vigil Neuroscience, Inc. (-138.30%), less than Checkpoint Therapeutics, Inc. (916.24%), less than Revance Therapeutics, Inc. (49.59%), greater than G1 Therapeutics, Inc. (-92.13%), greater than Climb Bio, Inc. (-23.10%), greater than Y-mAbs Therapeutics, Inc. (-24.60%), greater than scPharmaceuticals Inc. (-2086.11%), greater than iTeos Therapeutics, Inc. (-35.52%), greater than SomaLogic, Inc. (-18.59%), less than Claritev Corporation (3.19%),

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