Orchard Therapeutics plc

Orchard Therapeutics plcverified

ORTX

Price:

$16.7

Market Cap:

$380.11M

Orchard Therapeutics plc, a biopharmaceutical company, develops gene therapies for serious and life-threatening rare diseases in the United Kingdom, European Union, and the United States. The company's gene therapy approach seeks to transform a patient's hematopoietic stem cells into a gene-modified cellular drug product to treat the patient's disease through a single administration. It provides Strimvelis, a gammaretroviral-based product for the treatment of adenosine deaminase-severe combined immunodeficiency (ADA-SCID). The company's clinical development products comprise OTL-101 for the treatment of ADA-SCID; OTL-200 to treat metachromatic leukodystrophy; OTL-103 for the treatment of Wis...[Read more]

Industry

Biotechnology

IPO Date

2018-10-31

Stock Exchange

NASDAQ

Ticker

ORTX

The PE Ratio as of November 2025 (TTM) for Orchard Therapeutics plc (ORTX) is -4.07

According to Orchard Therapeutics plc’s latest financial reports and current stock price. The company's current PE Ratio is -4.07. This represents a change of 282.60% compared to the average of -1.06 of the last 4 quarters.

Orchard Therapeutics plc (ORTX) Historical PE Ratio (quarterly & annually)

How has ORTX PE Ratio performed in the past?

The mean historical PE Ratio of Orchard Therapeutics plc over the last ten years is -4.81. The current -4.07 PE Ratio has changed 8.37% with respect to the historical average. Over the past ten years (40 quarters), ORTX's PE Ratio was at its highest in in the December 2022 quarter at 0.09. The PE Ratio was at its lowest in in the December 2018 quarter at -13.47.

Quarterly (TTM)
Annual

Average

-4.81

Median

-4.50

Minimum

-7.85

Maximum

-1.54

Orchard Therapeutics plc (ORTX) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Orchard Therapeutics plc PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 409.57%

Maximum Annual PE Ratio = -1.54

Minimum Annual Increase = -63.97%

Minimum Annual PE Ratio = -7.85

Quarterly (TTM)
Annual
YearPE RatioChange
2022-6.0133.43%
2021-4.5059.25%
2020-2.83-63.97%
2019-7.85409.57%
2018-1.54-56.71%
2017-3.56-51.98%

Orchard Therapeutics plc (ORTX) Average PE Ratio

How has ORTX PE Ratio performed in the past?

The current PE Ratio of Orchard Therapeutics plc (ORTX) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-4.45

5-year avg

-4.54

10-year avg

-4.81

Orchard Therapeutics plc (ORTX) PE Ratio vs. Peers

How is ORTX’s PE Ratio compared to its peers?

Orchard Therapeutics plc’s PE Ratio is greater than Vigil Neuroscience, Inc. (-4.16), less than Checkpoint Therapeutics, Inc. (-0.05), greater than Revance Therapeutics, Inc. (-5.24), greater than G1 Therapeutics, Inc. (-7.72), less than Climb Bio, Inc. (-2.50), greater than Y-mAbs Therapeutics, Inc. (-17.56), less than scPharmaceuticals Inc. (-3.32), less than iTeos Therapeutics, Inc. (-2.18), less than SomaLogic, Inc. (-3.54), less than Claritev Corporation (-1.78),

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