Vigil Neuroscience, Inc.

Vigil Neuroscience, Inc.verified

VIGL

Price:

$8.05

Market Cap:

$383.88M

Vigil Neuroscience, Inc., a microglia-focused company, engages in the development of disease-modifying therapeutics for patients, caregivers, and families affected by rare and common neurodegenerative diseases. Its lead product candidate is VGL101, a fully human monoclonal antibody (mAb) that is designed to activate triggering receptor expressed on myeloid cells 2 (TREM2) which is in Phase I for the treatment of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, as well as for the treatment of cerebral adrenoleukodystrophy and alzheimer's disease. The company also develops a small molecule TREM2 agonist suitable for oral delivery to treat common neurodegenerative disea...[Read more]

Industry

Biotechnology

IPO Date

2022-01-07

Stock Exchange

NASDAQ

Ticker

VIGL

The ROE as of July 2025 (TTM) for Vigil Neuroscience, Inc. (VIGL) is -111.70%

According to Vigil Neuroscience, Inc.’s latest financial reports and current stock price. The company's current ROE is -111.70%. This represents a change of 290.81% compared to the average of -28.58% of the last 4 quarters.

Vigil Neuroscience, Inc. (VIGL) Historical ROE (quarterly & annually)

How has VIGL ROE performed in the past?

The mean historical ROE of Vigil Neuroscience, Inc. over the last ten years is -12.26%. The current -111.70% ROE has changed 810.96% with respect to the historical average. Over the past ten years (40 quarters), VIGL's ROE was at its highest in in the September 2021 quarter at 18.76%. The ROE was at its lowest in in the June 2021 quarter at -45.01%.

Quarterly (TTM)
Annual

Average

-12.26%

Median

-35.82%

Minimum

-117.62%

Maximum

100.93%

Vigil Neuroscience, Inc. (VIGL) ROE by Quarter and Year

Discovering the peaks and valleys of Vigil Neuroscience, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 98.46%

Maximum Annual ROE = 100.93%

Minimum Annual Increase = -157.51%

Minimum Annual ROE = -117.62%

Quarterly (TTM)
Annual
YearROEChange
2024-117.62%65.46%
2023-71.09%98.46%
2022-35.82%-157.51%
202162.28%-38.29%

Vigil Neuroscience, Inc. (VIGL) Average ROE

How has VIGL ROE performed in the past?

The current ROE of Vigil Neuroscience, Inc. (VIGL) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-74.84%

5-year avg

-12.26%

10-year avg

-12.26%

Vigil Neuroscience, Inc. (VIGL) ROE vs. Peers

How is VIGL’s ROE compared to its peers?

Vigil Neuroscience, Inc.’s ROE is greater than PepGen Inc. (-81.26%), greater than Tyra Biosciences, Inc. (-27.45%), less than Entrada Therapeutics, Inc. (5.84%), greater than Pharvaris N.V. (-54.35%), greater than Rallybio Corporation (-72.31%), greater than Xilio Therapeutics, Inc. (-198.52%), greater than Edgewise Therapeutics, Inc. (-30.95%),

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