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NASDAQ · ORKABiotechnologyUpdated Nov 2, 2026

Oruka Therapeutics, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Oruka Therapeutics, Inc. (ORKA) is -20.76%

According to Oruka Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -20.76%. This represents a change of 265.51% compared to the average of -5.68% of the last 4 quarters.

Oruka Therapeutics, Inc. (ORKA) Historical ROE (quarterly & annually)

How has ORKA ROE performed in the past?

The mean historical ROE of Oruka Therapeutics, Inc. over the last ten years is -59.89%. The current -20.76% ROE has changed -65.33% with respect to the historical average. Over the past ten years (40 quarters), ORKA's ROE was at its highest in in the December 2022 quarter at -2.82%. The ROE was at its lowest in in the June 2024 quarter at -68.29%.

Quarterly (TTM)
Annual

Average

-59.89%

Median

-30.84%

Minimum

-179.95%

Maximum

-14.42%

Oruka Therapeutics, Inc. (ORKA) ROE by Quarter and Year

Discovering the peaks and valleys of Oruka Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 146.46%

Maximum Annual ROE = -14.42%

Minimum Annual Increase = -70.94%

Minimum Annual ROE = -179.95%

Quarterly (TTM)
Annual
YearROEChange
2025-22.34%1.99%
2024-21.90%51.88%
2023-14.42%-39.45%
2022-23.82%-37.08%
2021-37.85%80.84%
2020-20.93%-70.94%
2019-72.04%-45.23%
2018-131.52%-26.92%
2017-179.95%142.88%
2016-74.09%146.46%

Oruka Therapeutics, Inc. (ORKA) Average ROE

How has ORKA ROE performed in the past?

The current ROE of Oruka Therapeutics, Inc. (ORKA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-19.56%

5-year avg

-24.07%

10-year avg

-59.89%

Oruka Therapeutics, Inc. (ORKA) ROE vs. Peers

How is ORKA’s ROE compared to its peers?

Oruka Therapeutics, Inc.’s ROE is less than AnaptysBio, Inc. (2.52%), less than Odyssey Therapeutics, Inc. (177.71%), greater than MoonLake Immunotherapeutics (-82.68%), greater than Aclaris Therapeutics, Inc. (-61.65%), greater than Alumis Inc. (-102.97%), greater than Dianthus Therapeutics, Inc. (-3.51%), greater than Connect Biopharma Holdings Limited (-150.47%), greater than Zura Bio Limited (-53.97%), greater than Xencor, Inc. (-28.66%), greater than Attovia Therapeutics, Inc. (-32.05%),

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