Alumis Inc.

Alumis Inc. - ROEverified

ALMS

Price:

$27.2

Market Cap:

$3.36B

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases. It also develops lonigutamab, a monoclonal antibody targeting IGF-1R for the treatment of thyroid eye diseases; and interferon regulatory factor 5 (IRF5) to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and c...[Read more]

Industry

Biotechnology

IPO Date

2024-06-28

Stock Exchange

NASDAQ

Ticker

ALMS

The ROE as of August 2026 (TTM) for Alumis Inc. (ALMS) is -54.63%

According to Alumis Inc.’s latest financial reports and current stock price. The company's current ROE is -54.63%. This represents a change of 242.41% compared to the average of -15.95% of the last 4 quarters.

Alumis Inc. (ALMS) Historical ROE (quarterly & annually)

How has ALMS ROE performed in the past?

The mean historical ROE of Alumis Inc. over the last ten years is -22.72%. The current -54.63% ROE has changed 140.48% with respect to the historical average. Over the past ten years (40 quarters), ALMS's ROE was at its highest in in the March 2024 quarter at 12.92%. The ROE was at its lowest in in the March 2025 quarter at -58.80%.

Quarterly (TTM)
Annual

Average

-22.72%

Median

-17.54%

Minimum

-113.12%

Maximum

57.33%

Alumis Inc. (ALMS) ROE by Quarter and Year

Discovering the peaks and valleys of Alumis Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 57.33%

Minimum Annual Increase = -347.61%

Minimum Annual ROE = -113.12%

Quarterly (TTM)
Annual
YearROEChange
2025-80.76%-28.61%
2024-113.12%-347.61%
202345.69%-20.31%

Alumis Inc. (ALMS) Average ROE

How has ALMS ROE performed in the past?

The current ROE of Alumis Inc. (ALMS) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-49.40%

5-year avg

-22.72%

10-year avg

-22.72%

Alumis Inc. (ALMS) ROE vs. Peers

How is ALMS’s ROE compared to its peers?

Alumis Inc.’s ROE is greater than RAPT Therapeutics, Inc. (-31.83%), greater than Neumora Therapeutics, Inc. Common Stock (-181.70%), less than ADC Therapeutics S.A. (65.27%), greater than Ocugen, Inc. (-127987.50%), greater than Eton Pharmaceuticals, Inc. (-5.68%), greater than Omeros Corporation (-54.39%), greater than Fulcrum Therapeutics, Inc. (-28.54%), greater than Lexicon Pharmaceuticals, Inc. (-18.64%), greater than Bicycle Therapeutics plc (-33.22%), greater than Lineage Cell Therapeutics, Inc. (-152.10%),

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