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NASDAQ · MNPRBiotechnologyUpdated Nov 4, 2026

Monopar Therapeutics Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Monopar Therapeutics Inc. (MNPR) is -13.08%

According to Monopar Therapeutics Inc.’s latest financial reports and current stock price. The company's current ROE is -13.08%. This represents a change of 298.30% compared to the average of -3.28% of the last 4 quarters.

Monopar Therapeutics Inc. (MNPR) Historical ROE (quarterly & annually)

How has MNPR ROE performed in the past?

The mean historical ROE of Monopar Therapeutics Inc. over the last ten years is -67.52%. The current -13.08% ROE has changed -80.63% with respect to the historical average. Over the past ten years (40 quarters), MNPR's ROE was at its highest in in the September 2016 quarter at 0%. The ROE was at its lowest in in the September 2017 quarter at -145.00%.

Quarterly (TTM)
Annual

Average

-67.52%

Median

-44.27%

Minimum

-172.10%

Maximum

-9.95%

Monopar Therapeutics Inc. (MNPR) ROE by Quarter and Year

Discovering the peaks and valleys of Monopar Therapeutics Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 310.95%

Maximum Annual ROE = -9.95%

Minimum Annual Increase = -81.17%

Minimum Annual ROE = -172.10%

Quarterly (TTM)
Annual
YearROEChange
2025-9.95%-64.86%
2024-28.32%-81.17%
2023-150.37%44.28%
2022-104.22%116.85%
2021-48.06%19.62%
2020-40.18%20.09%
2019-33.46%-28.29%
2018-46.66%-72.89%
2017-172.10%310.95%
2016-41.88%67.89%

Monopar Therapeutics Inc. (MNPR) Average ROE

How has MNPR ROE performed in the past?

The current ROE of Monopar Therapeutics Inc. (MNPR) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-62.88%

5-year avg

-68.18%

10-year avg

-67.52%

Monopar Therapeutics Inc. (MNPR) ROE vs. Peers

How is MNPR’s ROE compared to its peers?

Monopar Therapeutics Inc.’s ROE is less than ADC Therapeutics S.A. (44.63%), less than Actinium Pharmaceuticals, Inc. (83.42%), greater than ALX Oncology Holdings Inc. (-90.30%), greater than Bicycle Therapeutics plc (-26.02%), greater than Xencor, Inc. (-21.29%), greater than MacroGenics, Inc. (-31.27%), greater than Zymeworks Inc. (-72.07%), greater than Immunome, Inc. (-50.56%), greater than Compass Therapeutics, Inc. (-38.71%), less than Innate Pharma S.A. (152.56%),

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