Milestone Pharmaceuticals Inc.

Milestone Pharmaceuticals Inc.verified

MIST

Price:

$2.64

Market Cap:

$224.85M

Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines. The company is developing etripamil, a novel channel blocker, which is in Phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia in the United States and Canada; and Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate. It has a license and collaboration agreement with Ji Xing Pharmaceuticals to develop and commercialize etripamil prophylactic and therapeutic uses in humans. The company was incorporated in 2003 and is headquartered in Montréal, Canada.

Industry

Biotechnology

IPO Date

2019-05-09

Stock Exchange

NASDAQ

Ticker

MIST

The ROE as of December 2025 (TTM) for Milestone Pharmaceuticals Inc. (MIST) is -1885.07%

According to Milestone Pharmaceuticals Inc.’s latest financial reports and current stock price. The company's current ROE is -1885.07%. This represents a change of -2470.43% compared to the average of 79.52% of the last 4 quarters.

Milestone Pharmaceuticals Inc. (MIST) Historical ROE (quarterly & annually)

How has MIST ROE performed in the past?

The mean historical ROE of Milestone Pharmaceuticals Inc. over the last ten years is -101.53%. The current -1885.07% ROE has changed 1.76% with respect to the historical average. Over the past ten years (40 quarters), MIST's ROE was at its highest in in the March 2025 quarter at 339.07%. The ROE was at its lowest in in the December 2024 quarter at -94.04%.

Quarterly (TTM)
Annual

Average

-101.53%

Median

-42.96%

Minimum

-355.88%

Maximum

41.99%

Milestone Pharmaceuticals Inc. (MIST) ROE by Quarter and Year

Discovering the peaks and valleys of Milestone Pharmaceuticals Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 313.28%

Maximum Annual ROE = 41.99%

Minimum Annual Increase = -214.44%

Minimum Annual ROE = -355.88%

Quarterly (TTM)
Annual
YearROEChange
2024-315.81%-11.26%
2023-355.88%313.28%
2022-86.11%127.44%
2021-37.86%8.45%
2020-34.91%-27.36%
2019-48.06%-214.44%
201841.99%72.00%

Milestone Pharmaceuticals Inc. (MIST) Average ROE

How has MIST ROE performed in the past?

The current ROE of Milestone Pharmaceuticals Inc. (MIST) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-252.60%

5-year avg

-166.12%

10-year avg

-101.53%

Milestone Pharmaceuticals Inc. (MIST) ROE vs. Peers

How is MIST’s ROE compared to its peers?

Milestone Pharmaceuticals Inc.’s ROE is less than Rani Therapeutics Holdings, Inc. (3.37%), greater than Molecular Partners AG (-50.31%), greater than Applied Therapeutics, Inc. (-65.63%), greater than Cardiff Oncology, Inc. (-77.23%), greater than Elicio Therapeutics, Inc. (-5657.87%), greater than Cybin Inc. (-41.48%), greater than Innate Pharma S.A. (-658.91%), greater than Corbus Pharmaceuticals Holdings, Inc. (-43.65%), greater than Cassava Sciences, Inc. (-80.34%), greater than PepGen Inc. (-92.51%),

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