Applied Therapeutics, Inc.

Applied Therapeutics, Inc. - ROEverified

APLT

Price:

$0.103

Market Cap:

$14.86M

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical firm dedicated to developing innovative treatments for cardiovascular conditions, galactosemia, and various diabetes-related complications. The company's primary drug candidate, AT-007, has successfully concluded Phase 1/2 studies for galactosemia in healthy adult volunteers and is presently in a pediatric clinical study for the same indication in children. Additionally, AT-007 is being investigated for its potential to address sorbitol dehydrogenase deficiency and phosphomannomutase enzyme-CDG. Another key compound, AT-001, is currently undergoing pivotal Phase III clinical trials. This therapy is being evaluated for its effic...[Read more]

Industry

Biotechnology

IPO Date

2019-05-14

Stock Exchange

NASDAQ

Ticker

APLT

The ROE as of June 2026 (TTM) for Applied Therapeutics, Inc. (APLT) is -65.63%

According to Applied Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -65.63%. This represents a change of -108.00% compared to the average of 820.10% of the last 4 quarters.

Applied Therapeutics, Inc. (APLT) Historical ROE (quarterly & annually)

How has APLT ROE performed in the past?

The mean historical ROE of Applied Therapeutics, Inc. over the last ten years is -242.24%. The current -65.63% ROE has changed -72.91% with respect to the historical average. Over the past ten years (40 quarters), APLT's ROE was at its highest in in the September 2025 quarter at 3.39%. The ROE was at its lowest in in the September 2024 quarter at -1164.14%.

Quarterly (TTM)
Annual

Average

-242.24%

Median

-127.13%

Minimum

-2031.72%

Maximum

698.49%

Applied Therapeutics, Inc. (APLT) ROE by Quarter and Year

Discovering the peaks and valleys of Applied Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 1.10%

Maximum Annual ROE = 698.49%

Minimum Annual Increase = -196.61%

Minimum Annual ROE = -2031.72%

Quarterly (TTM)
Annual
YearROEChange
2024-185.29%-126.53%
2023698.49%-134.38%
2022-2031.72%1.10%
2021-168.83%47.23%
2020-114.67%-17.85%
2019-139.58%33.64%
2018-104.44%-196.61%

Applied Therapeutics, Inc. (APLT) Average ROE

How has APLT ROE performed in the past?

The current ROE of Applied Therapeutics, Inc. (APLT) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-506.17%

5-year avg

-360.40%

10-year avg

-242.24%

Applied Therapeutics, Inc. (APLT) ROE vs. Peers

How is APLT’s ROE compared to its peers?

Applied Therapeutics, Inc.’s ROE is greater than Molecular Partners AG (-66.19%), greater than Elicio Therapeutics, Inc. (-2748.16%), greater than Corbus Pharmaceuticals Holdings, Inc. (-70.89%), greater than Cardiff Oncology, Inc. (-95.50%), greater than PepGen Inc. (-59.89%), greater than Milestone Pharmaceuticals Inc. (-339.38%), greater than Rani Therapeutics Holdings, Inc. (-245.45%), greater than Nkarta, Inc. (-30.90%), greater than Cassava Sciences, Inc. (-99.85%), greater than Forte Biosciences, Inc. (-106.16%),

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