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NASDAQ · DSGNBiotechnologyUpdated Nov 2, 2026

Design Therapeutics, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Design Therapeutics, Inc. (DSGN) is -34.03%

According to Design Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -34.03%. This represents a change of 299.00% compared to the average of -8.53% of the last 4 quarters.

Design Therapeutics, Inc. (DSGN) Historical ROE (quarterly & annually)

How has DSGN ROE performed in the past?

The mean historical ROE of Design Therapeutics, Inc. over the last ten years is 3.33%. The current -34.03% ROE has changed -1120.70% with respect to the historical average. Over the past ten years (40 quarters), DSGN's ROE was at its highest in in the December 2020 quarter at 34.07%. The ROE was at its lowest in in the June 2026 quarter at -9.99%.

Quarterly (TTM)
Annual

Average

3.33%

Median

-19.34%

Minimum

-32.84%

Maximum

73.18%

Design Therapeutics, Inc. (DSGN) ROE by Quarter and Year

Discovering the peaks and valleys of Design Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 108.01%

Maximum Annual ROE = 73.18%

Minimum Annual Increase = -112.71%

Minimum Annual ROE = -32.84%

Quarterly (TTM)
Annual
YearROEChange
2025-32.84%60.34%
2024-20.48%-14.93%
2023-24.08%24.49%
2022-19.34%108.01%
2021-9.30%-112.71%
202073.18%30.20%

Design Therapeutics, Inc. (DSGN) Average ROE

How has DSGN ROE performed in the past?

The current ROE of Design Therapeutics, Inc. (DSGN) is greater than its 3-year, greater than its 5-year, and less than than its 10-year historical averages

3-year avg

-25.80%

5-year avg

-21.21%

10-year avg

3.33%

Design Therapeutics, Inc. (DSGN) ROE vs. Peers

How is DSGN’s ROE compared to its peers?

Design Therapeutics, Inc.’s ROE is greater than Larimar Therapeutics, Inc. (-137.39%), greater than Dyne Therapeutics, Inc. (-64.30%), greater than PepGen Inc. (-51.01%), greater than Solid Biosciences Inc. (-72.28%), greater than Stoke Therapeutics, Inc. (-67.30%), greater than Wave Life Sciences Ltd. (-44.48%), less than PTC Therapeutics, Inc. (57.10%), greater than Sarepta Therapeutics, Inc. (-9.96%), greater than Fulcrum Therapeutics, Inc. (-28.54%), greater than Ionis Pharmaceuticals, Inc. (-110.84%),

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