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NASDAQ · CLLSBiotechnologyUpdated Nov 2, 2026

Cellectis S.A. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Cellectis S.A. (CLLS) is -94.14%

According to Cellectis S.A.’s latest financial reports and current stock price. The company's current ROE is -94.14%. This represents a change of 222.60% compared to the average of -29.18% of the last 4 quarters.

Cellectis S.A. (CLLS) Historical ROE (quarterly & annually)

How has CLLS ROE performed in the past?

The mean historical ROE of Cellectis S.A. over the last ten years is -49.78%. The current -94.14% ROE has changed 89.13% with respect to the historical average. Over the past ten years (40 quarters), CLLS's ROE was at its highest in in the March 2024 quarter at 6.23%. The ROE was at its lowest in in the June 2026 quarter at -53.13%.

Quarterly (TTM)
Annual

Average

-49.78%

Median

-33.01%

Minimum

-119.32%

Maximum

-19.23%

Cellectis S.A. (CLLS) ROE by Quarter and Year

Discovering the peaks and valleys of Cellectis S.A. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 230.33%

Maximum Annual ROE = -19.23%

Minimum Annual Increase = -76.49%

Minimum Annual ROE = -119.32%

Quarterly (TTM)
Annual
YearROEChange
2025-92.67%230.33%
2024-28.05%-76.49%
2023-119.32%42.63%
2022-83.66%114.56%
2021-38.99%48.05%
2020-26.33%-8.49%
2019-28.78%49.68%
2018-19.23%-48.38%
2017-37.25%58.60%
2016-23.48%200.52%

Cellectis S.A. (CLLS) Average ROE

How has CLLS ROE performed in the past?

The current ROE of Cellectis S.A. (CLLS) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-80.02%

5-year avg

-72.54%

10-year avg

-49.78%

Cellectis S.A. (CLLS) ROE vs. Peers

How is CLLS’s ROE compared to its peers?

Cellectis S.A.’s ROE is greater than Alto Neuroscience, Inc. (-46.46%), greater than AC Immune S.A. (-99.17%), greater than Aldeyra The (-53.14%), greater than Amarin Corporation plc (-4.26%), greater than Alpha Tau Medical Ltd (-138.12%), greater than Larimar Therapeutics, Inc. (-137.39%), greater than Silence Therapeutics plc (-106.94%), greater than DBV Technologies S.A. (-121.83%), greater than Mereo BioPharma Group plc (-74.76%), greater than Korro Bio, Inc. (-114.26%),

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