Alto Neuroscience, Inc.

Alto Neuroscience, Inc.verified

ANRO

Price:

$13.38

Market Cap:

$415.67M

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company that engages in the psychiatry drug development business. The company develops ALTO-100 for the treatment of patients with major depressive disorder (MDD) and post-traumatic stress disorder; ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties to treat patients with MDD; and ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor for the treatment of cognitive impairment associated with schizophrenia. It also develops ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist to treat patients with MDD and higher levels of anhedonia, and ALTO...[Read more]

Industry

Biotechnology

IPO Date

2024-02-02

Stock Exchange

NYSE

Ticker

ANRO

The ROE as of December 2025 (TTM) for Alto Neuroscience, Inc. (ANRO) is -44.81%

According to Alto Neuroscience, Inc.’s latest financial reports and current stock price. The company's current ROE is -44.81%. This represents a change of 294.27% compared to the average of -11.36% of the last 4 quarters.

Alto Neuroscience, Inc. (ANRO) Historical ROE (quarterly & annually)

How has ANRO ROE performed in the past?

The mean historical ROE of Alto Neuroscience, Inc. over the last ten years is 38.97%. The current -44.81% ROE has changed -214.98% with respect to the historical average. Over the past ten years (40 quarters), ANRO's ROE was at its highest in in the December 2022 quarter at 19.92%. The ROE was at its lowest in in the March 2023 quarter at -20.40%.

Quarterly (TTM)
Annual

Average

38.97%

Median

61.40%

Minimum

-40.56%

Maximum

73.63%

Alto Neuroscience, Inc. (ANRO) ROE by Quarter and Year

Discovering the peaks and valleys of Alto Neuroscience, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 73.63%

Minimum Annual Increase = -180.07%

Minimum Annual ROE = -40.56%

Quarterly (TTM)
Annual
YearROEChange
2024-40.56%-180.07%
202350.65%-29.79%
202272.15%-2.00%

Alto Neuroscience, Inc. (ANRO) Average ROE

How has ANRO ROE performed in the past?

The current ROE of Alto Neuroscience, Inc. (ANRO) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

27.42%

5-year avg

38.97%

10-year avg

38.97%

Alto Neuroscience, Inc. (ANRO) ROE vs. Peers

How is ANRO’s ROE compared to its peers?

Alto Neuroscience, Inc.’s ROE is greater than Cellectis S.A. (-49.81%), greater than AC Immune S.A. (-49.04%), greater than Amarin Corporation plc (-18.34%), greater than Larimar Therapeutics, Inc. (-62.92%), greater than Contineum Therapeutics, Inc. Class A Common Stock (-32.33%), greater than Aldeyra Therapeutics, Inc. (-73.63%), greater than Alpha Tau Medical Ltd. (-56.45%), greater than Silence Therapeutics plc (-85.88%), greater than Korro Bio, Inc. (-61.51%), greater than DBV Technologies S.A. (-287.15%),

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