Apogee Therapeutics, Inc.

Apogee Therapeutics, Inc.verified

APGE

Price:

$75.5

Market Cap:

$4.14B

Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indications. The company primarily develops APG777, a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for AD; and APG808, an SQ extended half-life mAb for COPD. Its earlier-stage programs include APG990, an SQ extended half-life mAb for the treatment of AD; and APG222, an extended half-life SQ antibodies for AD. The company was founded in 2022 and is based in Waltham, Massachusetts.

Industry

Biotechnology

IPO Date

2023-07-14

Stock Exchange

NASDAQ

Ticker

APGE

The ROE as of December 2025 (TTM) for Apogee Therapeutics, Inc. (APGE) is -34.98%

According to Apogee Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -34.98%. This represents a change of 282.73% compared to the average of -9.14% of the last 4 quarters.

Apogee Therapeutics, Inc. (APGE) Historical ROE (quarterly & annually)

How has APGE ROE performed in the past?

The mean historical ROE of Apogee Therapeutics, Inc. over the last ten years is -25.17%. The current -34.98% ROE has changed 38.95% with respect to the historical average. Over the past ten years (40 quarters), APGE's ROE was at its highest in in the June 2023 quarter at 26.53%. The ROE was at its lowest in in the September 2025 quarter at -11.09%.

Quarterly (TTM)
Annual

Average

-25.17%

Median

-25.41%

Minimum

-28.00%

Maximum

-22.11%

Apogee Therapeutics, Inc. (APGE) ROE by Quarter and Year

Discovering the peaks and valleys of Apogee Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 14.95%

Maximum Annual ROE = -22.11%

Minimum Annual Increase = -21.06%

Minimum Annual ROE = -28.00%

Quarterly (TTM)
Annual
YearROEChange
2024-25.41%14.95%
2023-22.11%-21.06%

Apogee Therapeutics, Inc. (APGE) Average ROE

How has APGE ROE performed in the past?

The current ROE of Apogee Therapeutics, Inc. (APGE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-25.17%

5-year avg

-25.17%

10-year avg

-25.17%

Apogee Therapeutics, Inc. (APGE) ROE vs. Peers

How is APGE’s ROE compared to its peers?

Apogee Therapeutics, Inc.’s ROE is greater than Centessa Pharmaceuticals plc (-56.47%), greater than Xenon Pharmaceuticals Inc. (-38.50%), greater than ASCENTAGE PHARMA GROUP INTERNATIONAL (-249.24%), greater than Ultragenyx Pharmaceutical Inc. (-414.17%), greater than Celcuity Inc. (-179.00%), greater than Zai Lab Limited (-27.32%), greater than CG Oncology, Inc. Common stock (-15.40%), greater than Legend Biotech Corporation (-30.95%), greater than Soleno Therapeutics, Inc. (-25.88%), greater than Disc Medicine, Inc. (-31.61%),

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