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NASDAQ · RAREBiotechnologyUpdated Nov 4, 2026

Ultragenyx Pharmaceutical Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Ultragenyx Pharmaceutical Inc. (RARE) is 213.22%

According to Ultragenyx Pharmaceutical Inc.’s latest financial reports and current stock price. The company's current ROE is 213.22%. This represents a change of 181.82% compared to the average of 75.66% of the last 4 quarters.

Ultragenyx Pharmaceutical Inc. (RARE) Historical ROE (quarterly & annually)

How has RARE ROE performed in the past?

The mean historical ROE of Ultragenyx Pharmaceutical Inc. over the last ten years is -21.53%. The current 213.22% ROE has changed -1090.58% with respect to the historical average. Over the past ten years (40 quarters), RARE's ROE was at its highest in in the December 2025 quarter at 161.25%. The ROE was at its lowest in in the September 2025 quarter at -1969.79%.

Quarterly (TTM)
Annual

Average

-21.53%

Median

-56.74%

Minimum

-222.95%

Maximum

718.75%

Ultragenyx Pharmaceutical Inc. (RARE) ROE by Quarter and Year

Discovering the peaks and valleys of Ultragenyx Pharmaceutical Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 307.79%

Maximum Annual ROE = 718.75%

Minimum Annual Increase = -422.38%

Minimum Annual ROE = -222.95%

Quarterly (TTM)
Annual
YearROEChange
2025718.75%-422.38%
2024-222.95%1.22%
2023-220.26%9.75%
2022-200.69%307.79%
2021-49.21%204.51%
2020-16.16%-73.76%
2019-61.60%89.81%
2018-32.45%-58.81%
2017-78.79%51.89%
2016-51.87%89.20%

Ultragenyx Pharmaceutical Inc. (RARE) Average ROE

How has RARE ROE performed in the past?

The current ROE of Ultragenyx Pharmaceutical Inc. (RARE) is less than than its 3-year, less than than its 5-year, and greater than its 10-year historical averages

3-year avg

91.85%

5-year avg

5.13%

10-year avg

-21.53%

Ultragenyx Pharmaceutical Inc. (RARE) ROE vs. Peers

How is RARE’s ROE compared to its peers?

Ultragenyx Pharmaceutical Inc.’s ROE is greater than BioMarin Pharmaceutical Inc. (-0.31%), greater than Mereo BioPharma Group plc (-74.76%), greater than Abeona Therapeutics Inc. (-41.69%), greater than REGENXBIO Inc. (-220.07%), less than PTC Therapeutics, Inc. (57.10%), less than BridgeBio Pharma, Inc. (26.76%), greater than Rocket Pharmaceuticals, Inc. (-5.76%), greater than uniQure N.V. (-96.34%), greater than 4D Molecular Therapeutics, Inc. (-41.33%), less than MeiraGTx Holdings plc (284.38%),

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