The PE Ratio as of December 2025 (TTM) for VYNE Therapeutics Inc. (VYNE) is -0.47

According to VYNE Therapeutics Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.47. This represents a change of -77.83% compared to the average of -2.12 of the last 4 quarters.

VYNE Therapeutics Inc. (VYNE) Historical PE Ratio (quarterly & annually)

How has VYNE PE Ratio performed in the past?

The mean historical PE Ratio of VYNE Therapeutics Inc. over the last ten years is -14.69. The current -0.47 PE Ratio has changed 220.04% with respect to the historical average. Over the past ten years (40 quarters), VYNE's PE Ratio was at its highest in in the March 2022 quarter at 1.93. The PE Ratio was at its lowest in in the September 2016 quarter at -48.54.

VYNE Therapeutics Inc. (VYNE) PE Ratio by Quarter and Year

Discovering the peaks and valleys of VYNE Therapeutics Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

VYNE Therapeutics Inc. (VYNE) Average PE Ratio

How has VYNE PE Ratio performed in the past?

The current PE Ratio of VYNE Therapeutics Inc. (VYNE) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

VYNE Therapeutics Inc. (VYNE) PE Ratio vs. Peers

How is VYNE’s PE Ratio compared to its peers?

VYNE Therapeutics Inc.’s PE Ratio is less than AIM ImmunoTech Inc. (-0.20), less than KALA BIO, Inc. (-0.19), less than Pasithea Therapeutics Corp. (-0.00), greater than Soligenix, Inc. (-0.50), greater than Alaunos Therapeutics, Inc. (-1947.11), less than Brainstorm Cell Therapeutics Inc. (-0.46), greater than Quoin Pharmaceuticals, Ltd. (-0.91), less than Ensysce Biosciences, Inc. (-0.43), greater than XTL Biopharmaceuticals Ltd. (-4.14), less than Matinas BioPharma Holdings, Inc. (-0.23),

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