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NASDAQ · VYNEBiotechnologyUpdated Oct 27, 2026

VYNE Therapeutics Inc. enterprise value

Company valuation, historical trends, and peer comparisons.

The Enterprise Value as of October 2026 (TTM) for VYNE Therapeutics Inc. (VYNE) is 155.28M

According to VYNE Therapeutics Inc.’s latest financial reports and current stock price. The company's current Enterprise Value is 155.28M. This represents a change of -16498.40% compared to the average of -946919.14 of the last 4 quarters.

VYNE Therapeutics Inc. (VYNE) Historical Enterprise Value (quarterly & annually)

How has VYNE Enterprise Value performed in the past?

The mean historical Enterprise Value of VYNE Therapeutics Inc. over the last ten years is 175.97M. The current 155.28M Enterprise Value has changed -11.76% with respect to the historical average. Over the past ten years (40 quarters), VYNE's Enterprise Value was at its highest in in the December 2016 quarter at 32.98B. The Enterprise Value was at its lowest in in the December 2022 quarter at -22848635.00.

Quarterly (TTM)
Annual

Average

175.97M

Median

81.30M

Minimum

-22305935.00

Maximum

655.59M

VYNE Therapeutics Inc. (VYNE) Enterprise Value by Quarter and Year

Discovering the peaks and valleys of VYNE Therapeutics Inc. Enterprise Value, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 220.37%

Maximum Annual Enterprise Value = 655.59M

Minimum Annual Increase = -1998.73%

Minimum Annual Enterprise Value = -22305935.00

Quarterly (TTM)
Annual
YearEnterprise ValueChange
2025786.99K-99.36%
2024122.85M-1998.73%
2023-6469910.00-70.99%
2022-22305935.00-310.65%
202110.59M-94.18%
2020182.10M42.94%
2019127.39M220.37%
201839.76M-93.88%
2017649.41M-0.94%
2016655.59M14.74%

VYNE Therapeutics Inc. (VYNE) Average Enterprise Value

How has VYNE Enterprise Value performed in the past?

The current Enterprise Value of VYNE Therapeutics Inc. (VYNE) is greater than its 3-year, greater than its 5-year, and less than than its 10-year historical averages

3-year avg

39.05M

5-year avg

21.09M

10-year avg

175.97M

VYNE Therapeutics Inc. (VYNE) Enterprise Value vs. Peers

How is VYNE’s Enterprise Value compared to its peers?

VYNE Therapeutics Inc.’s Enterprise Value is greater than AIM ImmunoTech Inc. (599.65K), greater than KALA BIO, Inc. (3.14M), greater than Pasithea Therapeutics Corp. (-33290412.00), greater than Soligenix, Inc. (-1640331.00), greater than Alaunos Therapeutics, Inc. (6.43M), greater than Brainstorm Cell Therapeutics Inc. (10.62M), greater than Quoin Pharmaceuticals, Ltd. (4.85M), greater than Ensysce Biosciences, Inc. (7.40M), greater than XTL Biopharmaceuticals Ltd. (4.58M), greater than Matinas BioPharma Holdings, Inc. (-332192.00),

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