Rhythm Pharmaceuticals, Inc.

Rhythm Pharmaceuticals, Inc.verified

RYTM

Price:

$88.38

Market Cap:

$6.06B

Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company with commercial products, dedicated to the discovery, development, and market launch of therapies addressing rare genetic conditions that cause obesity. Its leading pharmaceutical, IMCIVREE, functions as a powerful agonist of the melanocortin-4 receptor (MC4R). This medication is indicated for treating obesity stemming from deficiencies in pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or the leptin receptor (LEPR), alongside its use in patients with Bardet-Biedl and Alström syndromes. Furthermore, the company is progressing setmelanotide (the active compound in IMCIVREE) through Phase II clinica...[Read more]

Industry

Biotechnology

IPO Date

2017-10-09

Stock Exchange

NASDAQ

Ticker

RYTM

The PE Ratio as of June 2026 (TTM) for Rhythm Pharmaceuticals, Inc. (RYTM) is -28.24

According to Rhythm Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -28.24. This represents a change of -3.05% compared to the average of -29.13 of the last 4 quarters.

Rhythm Pharmaceuticals, Inc. (RYTM) Historical PE Ratio (quarterly & annually)

How has RYTM PE Ratio performed in the past?

The mean historical PE Ratio of Rhythm Pharmaceuticals, Inc. over the last ten years is -14.83. The current -28.24 PE Ratio has changed 18.94% with respect to the historical average. Over the past ten years (40 quarters), RYTM's PE Ratio was at its highest in in the March 2021 quarter at 5.79. The PE Ratio was at its lowest in in the December 2025 quarter at -37.67.

Quarterly (TTM)
Annual

Average

-14.83

Median

-12.18

Minimum

-35.39

Maximum

-6.21

Rhythm Pharmaceuticals, Inc. (RYTM) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Rhythm Pharmaceuticals, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 170.12%

Maximum Annual PE Ratio = -6.21

Minimum Annual Increase = -51.17%

Minimum Annual PE Ratio = -35.39

Quarterly (TTM)
Annual
YearPE RatioChange
2025-35.39170.12%
2024-13.10-8.73%
2023-14.3671.31%
2022-8.3817.84%
2021-7.11-29.14%
2020-10.0461.55%
2019-6.21-44.80%
2018-11.25-51.17%
2017-23.0418.79%
2016-19.40-29.78%

Rhythm Pharmaceuticals, Inc. (RYTM) Average PE Ratio

How has RYTM PE Ratio performed in the past?

The current PE Ratio of Rhythm Pharmaceuticals, Inc. (RYTM) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

-20.95

5-year avg

-15.67

10-year avg

-14.83

Rhythm Pharmaceuticals, Inc. (RYTM) PE Ratio vs. Peers

How is RYTM’s PE Ratio compared to its peers?

Rhythm Pharmaceuticals, Inc.’s PE Ratio is less than Revolution Medicines, Inc. (-22.22), less than Akero Therapeutics, Inc. (-15.31), less than Atrium Therapeutics, Inc. (-3.27), greater than Protagonist Therapeutics, Inc. (-62.29), less than Stoke Therapeutics, Inc. (-11.08), less than uniQure N.V. (-8.28), less than Rocket Pharmaceuticals, Inc. (-1.47), less than Solid Biosciences Inc. (-4.09), less than MeiraGTx Holdings plc (-6.47), less than Nuvalent, Inc. (-21.54), less than Ventyx Biosciences, Inc. (-9.36), greater than Arcellx, Inc. (-28.30), less than Cullinan Therapeutics, Inc. (-3.67), less than Kiniksa Pharmaceuticals, Ltd. (54.35), less than Pliant Therapeutics, Inc. (-0.62), less than Syndax Pharmaceuticals, Inc. (-6.50), less than Viridian Therapeutics, Inc. (-4.63), less than Inozyme Pharma, Inc. (-4.67), less than Relay Therapeutics, Inc. (-9.77), less than Black Diamond Therapeutics, Inc. (-2.32), less than Arvinas, Inc. (-2.19),

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