Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc. - PE Ratioverified

KPTI

Price:

$9.02

Market Cap:

$204.42M

Karyopharm Therapeutics Inc. is a pharmaceutical company that has already brought products to market, focusing on identifying, advancing, and selling medications designed to disrupt nuclear export pathways. These drugs are primarily aimed at treating cancer and various other illnesses. The company's strategy involves researching, creating, and marketing innovative Selective Inhibitor of Nuclear Export (SINE) compounds, which operate by attaching to and deactivating the nuclear export protein XPO1. Their leading therapeutic, XPOVIO, holds approvals for several critical applications in adult patients: it is prescribed in combination with bortezomib and dexamethasone for multiple myeloma; along...[Read more]

Industry

Biotechnology

IPO Date

2013-11-06

Stock Exchange

NASDAQ

Ticker

KPTI

The PE Ratio as of June 2026 (TTM) for Karyopharm Therapeutics Inc. (KPTI) is -0.55

According to Karyopharm Therapeutics Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -0.55. This represents a change of -7.04% compared to the average of -0.59 of the last 4 quarters.

Karyopharm Therapeutics Inc. (KPTI) Historical PE Ratio (quarterly & annually)

How has KPTI PE Ratio performed in the past?

The mean historical PE Ratio of Karyopharm Therapeutics Inc. over the last ten years is -2.90. The current -0.55 PE Ratio has changed 1.80% with respect to the historical average. Over the past ten years (40 quarters), KPTI's PE Ratio was at its highest in in the December 2021 quarter at 47.21. The PE Ratio was at its lowest in in the December 2020 quarter at -98.26.

Quarterly (TTM)
Annual

Average

-2.90

Median

-3.10

Minimum

-5.94

Maximum

-0.41

Karyopharm Therapeutics Inc. (KPTI) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Karyopharm Therapeutics Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 99.49%

Maximum Annual PE Ratio = -0.41

Minimum Annual Increase = -61.91%

Minimum Annual PE Ratio = -5.94

Quarterly (TTM)
Annual
YearPE RatioChange
2025-0.41-61.91%
2024-1.0855.99%
2023-0.69-58.99%
2022-1.68-56.71%
2021-3.89-31.43%
2020-5.67-4.55%
2019-5.9499.49%
2018-2.98-12.68%
2017-3.416.13%
2016-3.22-19.36%

Karyopharm Therapeutics Inc. (KPTI) Average PE Ratio

How has KPTI PE Ratio performed in the past?

The current PE Ratio of Karyopharm Therapeutics Inc. (KPTI) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-0.73

5-year avg

-1.55

10-year avg

-2.90

Karyopharm Therapeutics Inc. (KPTI) PE Ratio vs. Peers

How is KPTI’s PE Ratio compared to its peers?

Karyopharm Therapeutics Inc.’s PE Ratio is less than Senti Biosciences, Inc. (-0.49), less than Barinthus Biotherapeutics plc (-0.51), less than CEL-SCI Corporation (-0.30), greater than X4 Pharmaceuticals, Inc. (-0.93), greater than Aligos Therapeutics, Inc. (-0.61), less than FibroGen, Inc. (0.16), greater than INmune Bio, Inc. (-0.86), greater than Mersana Therapeutics, Inc. (-2.07), less than Medicus Pharma Ltd. Common Stock (-0.21), greater than Telomir Pharmaceuticals, Inc. Common Stock (-4.83),

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