The PE Ratio as of December 2025 (TTM) for Cyclerion Therapeutics, Inc. (CYCN) is -2.43

According to Cyclerion Therapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -2.43. This represents a change of 60.75% compared to the average of -1.51 of the last 4 quarters.

Cyclerion Therapeutics, Inc. (CYCN) Historical PE Ratio (quarterly & annually)

How has CYCN PE Ratio performed in the past?

The mean historical PE Ratio of Cyclerion Therapeutics, Inc. over the last ten years is -2.10. The current -2.43 PE Ratio has changed 11.50% with respect to the historical average. Over the past ten years (40 quarters), CYCN's PE Ratio was at its highest in in the December 2024 quarter at 3.87. The PE Ratio was at its lowest in in the June 2025 quarter at -6.90.

Cyclerion Therapeutics, Inc. (CYCN) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Cyclerion Therapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Cyclerion Therapeutics, Inc. (CYCN) Average PE Ratio

How has CYCN PE Ratio performed in the past?

The current PE Ratio of Cyclerion Therapeutics, Inc. (CYCN) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

Cyclerion Therapeutics, Inc. (CYCN) PE Ratio vs. Peers

How is CYCN’s PE Ratio compared to its peers?

Cyclerion Therapeutics, Inc.’s PE Ratio is greater than Alaunos Therapeutics, Inc. (-1947.11), greater than XTL Biopharmaceuticals Ltd. (-4.14), greater than Polyrizon Ltd. (-21.85), less than Quoin Pharmaceuticals, Ltd. (-0.91), less than Pasithea Therapeutics Corp. (-0.00), less than Radiopharm Theranostics Limited (0), less than VYNE Therapeutics Inc. (-0.48), less than NovaBay Pharmaceuticals, Inc. (1.91), less than Addex Therapeutics Ltd (-0.90), less than AIM ImmunoTech Inc. (-0.20),

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