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NASDAQ · TSHABiotechnologyUpdated Nov 2, 2026

Taysha Gene Therapies, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Taysha Gene Therapies, Inc. (TSHA) is -56.19%

According to Taysha Gene Therapies, Inc.’s latest financial reports and current stock price. The company's current ROE is -56.19%. This represents a change of 285.68% compared to the average of -14.57% of the last 4 quarters.

Taysha Gene Therapies, Inc. (TSHA) Historical ROE (quarterly & annually)

How has TSHA ROE performed in the past?

The mean historical ROE of Taysha Gene Therapies, Inc. over the last ten years is -2455.08%. The current -56.19% ROE has changed -97.71% with respect to the historical average. Over the past ten years (40 quarters), TSHA's ROE was at its highest in in the June 2020 quarter at 241.91%. The ROE was at its lowest in in the December 2022 quarter at -5871.76%.

Quarterly (TTM)
Annual

Average

-2455.08%

Median

-124.85%

Minimum

-17493.57%

Maximum

825.93%

Taysha Gene Therapies, Inc. (TSHA) ROE by Quarter and Year

Discovering the peaks and valleys of Taysha Gene Therapies, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 9.46%

Maximum Annual ROE = 825.93%

Minimum Annual Increase = -102.07%

Minimum Annual ROE = -17493.57%

Quarterly (TTM)
Annual
YearROEChange
2025-44.14%-64.65%
2024-124.85%-16.14%
2023-148.88%-99.15%
2022-17493.57%9.46%
2021-182.97%969.32%
2020-17.11%-102.07%

Taysha Gene Therapies, Inc. (TSHA) Average ROE

How has TSHA ROE performed in the past?

The current ROE of Taysha Gene Therapies, Inc. (TSHA) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-105.96%

5-year avg

-3598.88%

10-year avg

-2455.08%

Taysha Gene Therapies, Inc. (TSHA) ROE vs. Peers

How is TSHA’s ROE compared to its peers?

Taysha Gene Therapies, Inc.’s ROE is greater than Neurogene Inc. (-45.11%), greater than 4D Molecular Therapeutics, Inc. (-41.33%), greater than Voyager Therapeutics, Inc. (-57.92%), greater than Abeona Therapeutics Inc. (-41.69%), greater than Passage Bio, Inc. (-218.59%), greater than REGENXBIO Inc. (-220.07%), greater than Rocket Pharmaceuticals, Inc. (-5.76%), greater than Sarepta Therapeutics, Inc. (-9.96%), greater than Benitec Biopharma Inc. (-28.41%),

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