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NASDAQ · SPTXBiotechnologyUpdated Nov 2, 2026

Seaport Therapeutics, Inc. Common Stock ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Seaport Therapeutics, Inc. Common Stock (SPTX) is -48.72%

According to Seaport Therapeutics, Inc. Common Stock’s latest financial reports and current stock price. The company's current ROE is -48.72%. This represents a change of -28127.07% compared to the average of 0.17% of the last 4 quarters.

Seaport Therapeutics, Inc. Common Stock (SPTX) Historical ROE (quarterly & annually)

How has SPTX ROE performed in the past?

The mean historical ROE of Seaport Therapeutics, Inc. Common Stock over the last ten years is 80.91%. The current -48.72% ROE has changed -160.21% with respect to the historical average. Over the past ten years (40 quarters), SPTX's ROE was at its highest in in the March 2026 quarter at 21.98%. The ROE was at its lowest in in the June 2026 quarter at -14.81%.

Quarterly (TTM)
Annual

Average

80.91%

Median

80.91%

Minimum

80.91%

Maximum

80.91%

Seaport Therapeutics, Inc. Common Stock (SPTX) ROE by Quarter and Year

Discovering the peaks and valleys of Seaport Therapeutics, Inc. Common Stock ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 80.91%

Minimum Annual Increase = 0%

Minimum Annual ROE = 80.91%

Quarterly (TTM)
Annual
YearROEChange

Seaport Therapeutics, Inc. Common Stock (SPTX) Average ROE

How has SPTX ROE performed in the past?

The current ROE of Seaport Therapeutics, Inc. Common Stock (SPTX) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

80.91%

5-year avg

80.91%

10-year avg

80.91%

Seaport Therapeutics, Inc. Common Stock (SPTX) ROE vs. Peers

How is SPTX’s ROE compared to its peers?

Seaport Therapeutics, Inc. Common Stock’s ROE is greater than LB Pharmaceuticals Inc Common Stock (-25.91%), greater than Rapport Therapeutics, Inc. Common Stock (-29.02%), greater than Neumora Therapeutics, Inc. Common Stock (-242.28%), greater than MapLight Therapeutics, Inc. (-63.84%), greater than GH Research PLC (-20.86%), greater than Vanda Pharmaceuticals Inc. (-106.94%), greater than Quantum BioPharma Ltd. (-413.07%), greater than Pasithea Therapeutics Corp. (-49.49%), greater than Contineum Therapeutics, Inc. (-24.73%), greater than Serina Therapeutics, Inc. (-222.42%),

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