Senti Biosciences, Inc.
SNTI
Price:
$2.22
Market Cap:
$58.36M
Senti Biosciences, Inc. operates as a gene circuit company. The company develops cell and gene therapies engineered with gene circuits that are designed to reprogram cells with biological logic to sense inputs, compute decisions, and respond to respective cellular environments. Its synthetic biology platform utilizes off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to target particularly challenging liquid and solid tumor oncology indications. The company's lead programs include SENTI-202, a Logic Gated OR+NOT off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells, while sparing the healthy bone marrow; and SENTI-301, a mult...[Read more]
Industry
Biotechnology
IPO Date
2021-05-26
Stock Exchange
NASDAQ
Ticker
SNTI
PE Ratio
[-0.77]
ROE
[-197.68%]
Current Ratio
[1.51]
Dividend Yield
[0%]
Enterprise Value
[76.24M]
Dividend History
The ROE as of December 2025 (TTM) for Senti Biosciences, Inc. (SNTI) is -197.68%
According to Senti Biosciences, Inc.’s latest financial reports and current stock price. The company's current ROE is -197.68%. This represents a change of 145.09% compared to the average of -80.65% of the last 4 quarters.
Senti Biosciences, Inc. (SNTI) Historical ROE (quarterly & annually)
How has SNTI ROE performed in the past?
The mean historical ROE of Senti Biosciences, Inc. over the last ten years is -94.33%. The current -197.68% ROE has changed 109.56% with respect to the historical average. Over the past ten years (40 quarters), SNTI's ROE was at its highest in in the December 2024 quarter at -2.38%. The ROE was at its lowest in in the September 2025 quarter at -223.20%.
Average
-94.33%
Median
-104.70%
Minimum
-205.82%
Maximum
33.83%
Senti Biosciences, Inc. (SNTI) ROE by Quarter and Year
Discovering the peaks and valleys of Senti Biosciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.
Maximum Annual Increase = 203.60%
Maximum Annual ROE = 33.83%
Minimum Annual Increase = -370.85%
Minimum Annual ROE = -205.82%
| Year | ROE | Change |
|---|---|---|
| 2024 | -205.82% | 48.21% |
| 2023 | -138.87% | 203.60% |
| 2022 | -45.74% | -50.08% |
| 2021 | -91.62% | -370.85% |
| 2020 | 33.83% | -128.73% |
Senti Biosciences, Inc. (SNTI) Average ROE
How has SNTI ROE performed in the past?
The current ROE of Senti Biosciences, Inc. (SNTI) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages
3-year avg
-130.14%
5-year avg
-89.64%
10-year avg
-94.33%
Senti Biosciences, Inc. (SNTI) ROE vs. Peers
How is SNTI’s ROE compared to its peers?
Senti Biosciences, Inc.’s ROE is less than Karyopharm Therapeutics Inc. (55.38%), greater than X4 Pharmaceuticals, Inc. (-375.31%), greater than Century Therapeutics, Inc. (-11.53%), greater than Barinthus Biotherapeutics plc (-70.19%), greater than Coeptis Therapeutics, Inc. (-133.20%), greater than CEL-SCI Corporation (-259.39%), greater than Cue Biopharma, Inc. (-230.13%), greater than Aligos Therapeutics, Inc. (-132.42%), greater than Genenta Science S.p.A. (-70.71%), greater than Medicus Pharma Ltd. Common Stock (-711.37%),
| Company | ROE | Market cap |
|---|---|---|
| 55.38% | $50.46M | |
| -375.31% | $43.35M | |
| -11.53% | $45.25M | |
| -70.19% | $29.44M | |
| -133.20% | $57.70M | |
| -259.39% | $43.22M | |
| -230.13% | $43.54M | |
| -132.42% | $62.09M | |
| -70.71% | $35.60M | |
| -711.37% | $42.30M |
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