The ROE as of December 2025 (TTM) for Sionna Therapeutics, Inc. (SION) is -62.72%

According to Sionna Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -62.72%. This represents a change of 66.69% compared to the average of -0.09% of the last 4 quarters.

Sionna Therapeutics, Inc. (SION) Historical ROE (quarterly & annually)

How has SION ROE performed in the past?

The mean historical ROE of Sionna Therapeutics, Inc. over the last ten years is 45.46%. The current -62.72% ROE has changed -237.99% with respect to the historical average. Over the past ten years (40 quarters), SION's ROE was at its highest in in the December 2023 quarter at 10.34%. The ROE was at its lowest in in the June 2025 quarter at -5.37%.

Sionna Therapeutics, Inc. (SION) ROE by Quarter and Year

Discovering the peaks and valleys of Sionna Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Sionna Therapeutics, Inc. (SION) Average ROE

How has SION ROE performed in the past?

The current ROE of Sionna Therapeutics, Inc. (SION) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

Sionna Therapeutics, Inc. (SION) ROE vs. Peers

How is SION’s ROE compared to its peers?

Sionna Therapeutics, Inc.’s ROE is greater than Janux Therapeutics, Inc. (-10.18%), greater than AbCellera Biologics Inc. (-16.95%), greater than Maze Therapeutics, Inc. (-44.62%), greater than Biohaven Ltd. (-389.88%), greater than Celldex Therapeutics, Inc. (-27.62%), greater than Vera Therapeutics, Inc. (-46.70%), less than Xeris Biopharma Holdings, Inc. (113.91%), greater than Zymeworks Inc. (-24.48%), greater than Ardelyx, Inc. (-36.91%), greater than Immunome, Inc. (-87.36%),

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