PIRS logo
NASDAQ · PIRSBiotechnologyUpdated Nov 4, 2026

Pieris Pharmaceuticals, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Pieris Pharmaceuticals, Inc. (PIRS) is -47.84%

According to Pieris Pharmaceuticals, Inc.’s latest financial reports and current stock price. The company's current ROE is -47.84%. This represents a change of 108.83% compared to the average of -22.91% of the last 4 quarters.

Pieris Pharmaceuticals, Inc. (PIRS) Historical ROE (quarterly & annually)

How has PIRS ROE performed in the past?

The mean historical ROE of Pieris Pharmaceuticals, Inc. over the last ten years is -94.28%. The current -47.84% ROE has changed -49.25% with respect to the historical average. Over the past ten years (40 quarters), PIRS's ROE was at its highest in in the December 2017 quarter at 65.01%. The ROE was at its lowest in in the September 2017 quarter at -154.86%.

Quarterly (TTM)
Annual

Average

-94.28%

Median

-91.05%

Minimum

-153.16%

Maximum

-27.85%

Pieris Pharmaceuticals, Inc. (PIRS) ROE by Quarter and Year

Discovering the peaks and valleys of Pieris Pharmaceuticals, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 435.33%

Maximum Annual ROE = -27.85%

Minimum Annual Increase = -69.64%

Minimum Annual ROE = -153.16%

Quarterly (TTM)
Annual
YearROEChange
2025-149.07%435.33%
2024-27.85%-69.64%
2023-91.72%-18.03%
2022-111.90%30.97%
2021-85.44%-28.79%
2020-119.99%159.39%
2019-46.26%-30.95%
2018-66.99%-56.26%
2017-153.16%69.47%
2016-90.38%100.11%

Pieris Pharmaceuticals, Inc. (PIRS) Average ROE

How has PIRS ROE performed in the past?

The current ROE of Pieris Pharmaceuticals, Inc. (PIRS) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-89.55%

5-year avg

-93.20%

10-year avg

-94.28%

Pieris Pharmaceuticals, Inc. (PIRS) ROE vs. Peers

How is PIRS’s ROE compared to its peers?

Pieris Pharmaceuticals, Inc.’s ROE is greater than COSCIENS Biopharma Inc. (-48.52%), less than Nymox Pharmaceutical Corporation (53.17%), greater than Alpha Compute Corp (-748.11%), less than Traws Pharma, Inc. (353.43%), greater than MEI Pharma, Inc. (-97.27%), less than Kineta, Inc. (374.84%), greater than MetaVia Inc. (-209.67%), greater than PHAXIAM Therapeutics S.A. (-95.68%), greater than Elevation Oncology, Inc. (-77.48%), greater than Imunon, Inc. (-314.89%),

Build a custom stock screener for Pieris Pharmaceuticals, Inc. (PIRS) and other stocks

One of the best ways to find valuable stocks to invest in is to build a custom made screener in your Excel or Google Sheets spreadsheet. This allows you to compare thousands of companies like Pieris Pharmaceuticals, Inc. using the financials and key metrics that matter to you in a single view.

The easiest way to set this up is to use the Wisesheets add-on and set your spreadsheet like this:

Custom stock screener in Wisesheets

Covering all these metrics from financial, data, dividend data, key metrics and more you can get all the data you want for over 50+ exchanges worldwide.

Get your free trial here.

Pieris Pharmaceuticals, Inc. (PIRS) and other stocks custom spreadsheet templates

The easiest way to analyze a company like Pieris Pharmaceuticals, Inc. or any others is to create a spreadsheet model that automatically retrieves all of the stock data you need.

Using Wisesheets you can set up a spreadsheet model like this with simple spreadsheet formulas. If you change the ticker you can get all of the data automatically updated for you.

Custom stock templates in Wisesheets

Whether you need live data, historical price data, financials, dividend data, key metrics, analyst estimates, or anything else...Wisesheets has you covered.

Frequently asked questions❓

What is the ROE?

How can you use the ROE?

What is Pieris Pharmaceuticals, Inc.'s ROE?

How is the ROE calculated for Pieris Pharmaceuticals, Inc. (PIRS)?

What is the highest ROE for Pieris Pharmaceuticals, Inc. (PIRS)?

What is the 3-year average ROE for Pieris Pharmaceuticals, Inc. (PIRS)?

What is the 5-year average ROE for Pieris Pharmaceuticals, Inc. (PIRS)?

How does the current ROE for Pieris Pharmaceuticals, Inc. (PIRS) compare to its historical average?