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NASDAQ · PBYIBiotechnologyUpdated Nov 4, 2026

Puma Biotechnology, Inc. ROE

Profitability, historical returns, and peer comparisons.

The ROE as of November 2026 (TTM) for Puma Biotechnology, Inc. (PBYI) is 20.85%

According to Puma Biotechnology, Inc.’s latest financial reports and current stock price. The company's current ROE is 20.85%. This represents a change of 297.70% compared to the average of 5.24% of the last 4 quarters.

Puma Biotechnology, Inc. (PBYI) Historical ROE (quarterly & annually)

How has PBYI ROE performed in the past?

The mean historical ROE of Puma Biotechnology, Inc. over the last ten years is 85.26%. The current 20.85% ROE has changed -75.55% with respect to the historical average. Over the past ten years (40 quarters), PBYI's ROE was at its highest in in the September 2020 quarter at 6.95%. The ROE was at its lowest in in the March 2020 quarter at -180.58%.

Quarterly (TTM)
Annual

Average

85.26%

Median

11.94%

Minimum

-547.84%

Maximum

1.19%

Puma Biotechnology, Inc. (PBYI) ROE by Quarter and Year

Discovering the peaks and valleys of Puma Biotechnology, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 436.39%

Maximum Annual ROE = 1.19%

Minimum Annual Increase = -332.89%

Minimum Annual ROE = -547.84%

Quarterly (TTM)
Annual
YearROEChange
202523.87%-27.37%
202432.87%-18.65%
202340.40%436.39%
20220.01%-100.00%
20211.19%18.11%
20201.01%-332.89%
2019-432.89%30.73%
2018-331.14%-39.56%
2017-547.84%316.44%
2016-131.55%13.25%

Puma Biotechnology, Inc. (PBYI) Average ROE

How has PBYI ROE performed in the past?

The current ROE of Puma Biotechnology, Inc. (PBYI) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

32.38%

5-year avg

257.58%

10-year avg

85.26%

Puma Biotechnology, Inc. (PBYI) ROE vs. Peers

How is PBYI’s ROE compared to its peers?

Puma Biotechnology, Inc.’s ROE is greater than Verastem, Inc. (-467.49%), greater than Black Diamond Therapeutics, Inc. (-38.80%), greater than ArriVent BioPharma, Inc. (-50.26%), less than Oncolytics Biotech Inc. (1.02%), greater than NovaBridge Biosciences (-1.45%), greater than ORIC Pharmaceuticals, Inc. (-35.35%), greater than Nuvation Bio Inc. (-49.73%), greater than Tango Therapeutics, Inc. (-25.74%), greater than MacroGenics, Inc. (-31.27%), greater than Cardiff Oncology, Inc. (-103.08%),

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