Klotho Neurosciences, Inc.

Klotho Neurosciences, Inc.verified

KLTO

Price:

$0.49

Market Cap:

$25.82M

Klotho Neurosciences, Inc., a biopharmaceutical company, develops medicines for the treatment of cancer, cardiovascular, and neurodegenerative disorders. Its lead gene therapy product candidates include AMI-101 for the treatment or prevention of Alzheimer's disease; and AMI-202 to treat and prevent amyotrophic lateral sclerosis. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. The company is based in Omaha, Nebraska.

Industry

Biotechnology

IPO Date

2022-04-29

Stock Exchange

NASDAQ

Ticker

KLTO

The ROE as of December 2025 (TTM) for Klotho Neurosciences, Inc. (KLTO) is -201.59%

According to Klotho Neurosciences, Inc.’s latest financial reports and current stock price. The company's current ROE is -201.59%. This represents a change of 36.26% compared to the average of -147.94% of the last 4 quarters.

Klotho Neurosciences, Inc. (KLTO) Historical ROE (quarterly & annually)

How has KLTO ROE performed in the past?

The mean historical ROE of Klotho Neurosciences, Inc. over the last ten years is -160.30%. The current -201.59% ROE has changed 25.76% with respect to the historical average. Over the past ten years (40 quarters), KLTO's ROE was at its highest in in the June 2024 quarter at 29.11%. The ROE was at its lowest in in the March 2025 quarter at -349.77%.

Quarterly (TTM)
Annual

Average

-160.30%

Median

-108.05%

Minimum

-518.87%

Maximum

-0.09%

Klotho Neurosciences, Inc. (KLTO) ROE by Quarter and Year

Discovering the peaks and valleys of Klotho Neurosciences, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 126.75%

Maximum Annual ROE = -0.09%

Minimum Annual Increase = -53.02%

Minimum Annual ROE = -518.87%

Quarterly (TTM)
Annual
YearROEChange
2024-518.87%319.31%
2023-123.74%143.76%
2022-50.76%-53.02%
2021-108.05%126.75%

Klotho Neurosciences, Inc. (KLTO) Average ROE

How has KLTO ROE performed in the past?

The current ROE of Klotho Neurosciences, Inc. (KLTO) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-231.12%

5-year avg

-160.30%

10-year avg

-160.30%

Klotho Neurosciences, Inc. (KLTO) ROE vs. Peers

How is KLTO’s ROE compared to its peers?

Klotho Neurosciences, Inc.’s ROE is greater than Cadrenal Therapeutics, Inc. Common Stock (-279.52%), greater than Rallybio Corporation (-71.66%), greater than Exicure, Inc. (-110.40%), less than Minerva Neurosciences, Inc. (-0.00%), greater than iBio, Inc. (-83.61%), less than NeuroSense Therapeutics Ltd. (2.72%), greater than Sonnet BioTherapeutics Holdings, Inc. (-4648.06%), greater than TAO Synergies Inc. (-256.58%), greater than MetaVia Inc. (-212.00%), greater than NeurAxis, Inc. (-340.23%),

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