Hillstream BioPharma, Inc.

Hillstream BioPharma, Inc.verified

HILS

Price:

$0.237

Market Cap:

$4.17M

Hillstream BioPharma, Inc., a pre-clinical biotechnology company, develops novel therapeutic candidates targeting ferroptosis, an anti-cancer mechanism resulting in iron mediated cell death (IMCD) for the treatment resistant cancers. The company's product candidate is HSB-1216, an IMCD inducer targeting solid tumors. It also develops HSB-888, a dual Quatramer loaded IMCD inducer coupled with its anthracycline analogue for solid tumors; HSB-510, a targeted bifunctional inhibitory compound in Quatramer with single digit nanomolar IC50 against PI3K-delta and HDAC6, which is also known to downregulate; and HSB-114, an immunotherapeutic agent, which uses its Quatramer technology to deliver tumor ...[Read more]

Industry

Biotechnology

IPO Date

2022-01-12

Stock Exchange

NASDAQ

Ticker

HILS

The ROE as of November 2025 (TTM) for Hillstream BioPharma, Inc. (HILS) is -1397.15%

According to Hillstream BioPharma, Inc.’s latest financial reports and current stock price. The company's current ROE is -1397.15%. This represents a change of 667.56% compared to the average of -182.03% of the last 4 quarters.

Hillstream BioPharma, Inc. (HILS) Historical ROE (quarterly & annually)

How has HILS ROE performed in the past?

The mean historical ROE of Hillstream BioPharma, Inc. over the last ten years is -164.46%. The current -1397.15% ROE has changed 749.53% with respect to the historical average. Over the past ten years (40 quarters), HILS's ROE was at its highest in in the March 2025 quarter at 311.99%. The ROE was at its lowest in in the December 2022 quarter at -28792.75%.

Quarterly (TTM)
Annual

Average

-164.46%

Median

-19.09%

Minimum

-932.79%

Maximum

72.19%

Hillstream BioPharma, Inc. (HILS) ROE by Quarter and Year

Discovering the peaks and valleys of Hillstream BioPharma, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 814.00%

Maximum Annual ROE = 72.19%

Minimum Annual Increase = -335.71%

Minimum Annual ROE = -932.79%

Quarterly (TTM)
Annual
YearROEChange
2024-932.79%814.00%
2023-102.06%-33.23%
2022-152.84%-335.71%
202164.84%1.51%
202063.88%-11.52%

Hillstream BioPharma, Inc. (HILS) Average ROE

How has HILS ROE performed in the past?

The current ROE of Hillstream BioPharma, Inc. (HILS) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-395.90%

5-year avg

-211.79%

10-year avg

-164.46%

Hillstream BioPharma, Inc. (HILS) ROE vs. Peers

How is HILS’s ROE compared to its peers?

Hillstream BioPharma, Inc.’s ROE is greater than TNF Pharmaceuticals, Inc. (-48.34%), less than Gamida Cell Ltd. (1.15%), less than Aptose Biosciences Inc. (123.88%), greater than Gritstone bio, Inc. (-124.41%), less than Altamira Therapeutics Ltd. (783.37%), greater than VivoSim Labs, Inc. (-33.01%), greater than Nabriva Therapeutics plc (-201.91%), greater than Atreca, Inc. (-77.59%), greater than Onconetix, Inc. (-839.59%), greater than Unity Biotechnology, Inc. (-273.74%),

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