Graphite Bio, Inc.

Graphite Bio, Inc.verified

GRPH

Price:

$3.18

Market Cap:

$204.43M

Graphite Bio, Inc. is a clinical-stage gene editing company dedicated to developing innovative therapeutic solutions for severe and life-threatening illnesses across the United States. Its primary investigational therapy, GPH101, is an autologous, gene-edited hematopoietic stem cell product specifically engineered to directly correct the underlying mutation causing sickle cell disease, thereby restoring normal adult hemoglobin production. The company's pipeline also features GPH201, intended for the treatment of X-linked severe combined immunodeficiency syndrome, and GPH301, an experimental candidate designed to address Gaucher disease, a genetic disorder characterized by a deficiency in the...[Read more]

Industry

Biotechnology

IPO Date

2021-06-25

Stock Exchange

NASDAQ

Ticker

GRPH

The ROE as of June 2026 (TTM) for Graphite Bio, Inc. (GRPH) is -46.82%

According to Graphite Bio, Inc.’s latest financial reports and current stock price. The company's current ROE is -46.82%. This represents a change of 313.51% compared to the average of -11.32% of the last 4 quarters.

Graphite Bio, Inc. (GRPH) Historical ROE (quarterly & annually)

How has GRPH ROE performed in the past?

The mean historical ROE of Graphite Bio, Inc. over the last ten years is 181.05%. The current -46.82% ROE has changed -125.86% with respect to the historical average. Over the past ten years (40 quarters), GRPH's ROE was at its highest in in the December 2020 quarter at 648.33%. The ROE was at its lowest in in the March 2026 quarter at -16.83%.

Quarterly (TTM)
Annual

Average

181.05%

Median

44.73%

Minimum

-28.88%

Maximum

697.68%

Graphite Bio, Inc. (GRPH) ROE by Quarter and Year

Discovering the peaks and valleys of Graphite Bio, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 14.10%

Maximum Annual ROE = 697.68%

Minimum Annual Increase = -132.31%

Minimum Annual ROE = -28.88%

Quarterly (TTM)
Annual
YearROEChange
2025-28.88%18.44%
2024-24.39%-132.31%
202375.47%68.72%
202244.73%-91.01%
2021497.82%-28.65%
2020697.68%14.10%

Graphite Bio, Inc. (GRPH) Average ROE

How has GRPH ROE performed in the past?

The current ROE of Graphite Bio, Inc. (GRPH) is less than than its 3-year, less than than its 5-year, and less than than its 10-year historical averages

3-year avg

7.40%

5-year avg

112.95%

10-year avg

181.05%

Graphite Bio, Inc. (GRPH) ROE vs. Peers

How is GRPH’s ROE compared to its peers?

Graphite Bio, Inc.’s ROE is greater than Theseus Pharmaceuticals, Inc. (-20.74%), greater than LakeShore Biopharma Co., Ltd (-18.43%), greater than Vaccitech plc (-63.87%), less than Zevra Therapeutics, Inc. (81.34%), greater than Alaunos Therapeutics, Inc. (-165.94%), greater than CARGO Therapeutics, Inc. Common Stock (-61.29%), greater than Spectrum Pharmaceuticals, Inc. (-207.06%), greater than F-star Therapeutics, Inc. (-44.74%), less than Graybug Vision, Inc. (4.09%), greater than eXoZymes, Inc. (-220.64%),

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