Clene Inc.

Clene Inc.verified

CLNN

Price:

$5.84

Market Cap:

$60.20M

Clene Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to the discovery, advancement, and market introduction of pioneering therapeutic agents utilizing clean-surfaced nanotechnology (CSN). CNM-Au8 stands as its flagship compound, currently under evaluation across a diverse range of clinical studies. This includes a pivotal Phase 2/3 study intended for regulatory submission in individuals battling amyotrophic lateral sclerosis (ALS). The company has successfully concluded a Phase 2 proof-of-concept trial for those with early manifestations of ALS. Furthermore, two open-label, investigator-blinded Phase 2 trials assessing brain energy metabolism have been finished...[Read more]

Industry

Biotechnology

IPO Date

2018-10-18

Stock Exchange

NASDAQ

Ticker

CLNN

The ROE as of June 2026 (TTM) for Clene Inc. (CLNN) is 233.93%

According to Clene Inc.’s latest financial reports and current stock price. The company's current ROE is 233.93%. This represents a change of 269.45% compared to the average of 63.32% of the last 4 quarters.

Clene Inc. (CLNN) Historical ROE (quarterly & annually)

How has CLNN ROE performed in the past?

The mean historical ROE of Clene Inc. over the last ten years is -751.87%. The current 233.93% ROE has changed -131.11% with respect to the historical average. Over the past ten years (40 quarters), CLNN's ROE was at its highest in in the June 2024 quarter at 1.35%. The ROE was at its lowest in in the March 2022 quarter at -662.07%.

Quarterly (TTM)
Annual

Average

-751.87%

Median

-77.32%

Minimum

-5653.08%

Maximum

444.85%

Clene Inc. (CLNN) ROE by Quarter and Year

Discovering the peaks and valleys of Clene Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 5.86%

Maximum Annual ROE = 444.85%

Minimum Annual Increase = -Infinity%

Minimum Annual ROE = -5653.08%

Quarterly (TTM)
Annual
YearROEChange
2025148.78%-66.56%
2024444.85%-220.32%
2023-369.71%-60.00%
2022-924.25%1.10%
2021-77.32%-98.63%
2020-5653.08%1.61%
2019-330.57%5.86%
2018-5.55%-Infinity%

Clene Inc. (CLNN) Average ROE

How has CLNN ROE performed in the past?

The current ROE of Clene Inc. (CLNN) is less than than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

74.64%

5-year avg

-155.53%

10-year avg

-751.87%

Clene Inc. (CLNN) ROE vs. Peers

How is CLNN’s ROE compared to its peers?

Clene Inc.’s ROE is greater than MacroGenics, Inc. (-147.80%), greater than Ovid Therapeutics Inc. (-22.51%), greater than Coya Therapeutics, Inc. (-57.26%), less than Oramed Pharmaceuticals Inc. (55.29%), greater than Whitehawk Therapeutics Inc (-79.63%), greater than Context Therapeutics Inc. (-59.95%), greater than Zentalis Pharmaceuticals, Inc. (-53.61%), greater than Shattuck Labs, Inc. (-60.73%), greater than Pliant Therapeutics, Inc. (-59.06%), greater than Connect Biopharma Holdings Limited (-49.43%),

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