Aileron Therapeutics, Inc.

Aileron Therapeutics, Inc.verified

ALRN

Price:

$2.11

Market Cap:

$35.75M

Aileron Therapeutics, Inc. operates as a clinical stage chemoprotection oncology company in the United States. The company is developing ALRN-6924, which is in Phase 1 trial for solid tumor and lymphoma; Phase 2a clinical trial to treat peripheral T-cell lymphoma; Phase I clinical trial for the treatment of acute myeloid leukemia (AML) and advanced myelodysplastic syndrome (MDS); Phase 1b trial to test the combination of ALRN-6924 and cytarabine, or Ara-C, in patients with MDS; and a Phase 2a combination trial of ALRN-6924 and palbociclib in patients with tumors harboring MDM2 amplifications co-amplifications, as well as for patients with p53-mutated small cell lung cancer that has completed...[Read more]

Industry

Biotechnology

IPO Date

2017-06-29

Stock Exchange

NASDAQ

Ticker

ALRN

The ROE as of November 2025 (TTM) for Aileron Therapeutics, Inc. (ALRN) is -217.16%

According to Aileron Therapeutics, Inc.’s latest financial reports and current stock price. The company's current ROE is -217.16%. This represents a change of 103.39% compared to the average of -106.77% of the last 4 quarters.

Aileron Therapeutics, Inc. (ALRN) Historical ROE (quarterly & annually)

How has ALRN ROE performed in the past?

The mean historical ROE of Aileron Therapeutics, Inc. over the last ten years is -11.62%. The current -217.16% ROE has changed 1.77% with respect to the historical average. Over the past ten years (40 quarters), ALRN's ROE was at its highest in in the March 2016 quarter at 0%. The ROE was at its lowest in in the June 2025 quarter at -226.80%.

Quarterly (TTM)
Annual

Average

-11.62%

Median

-0.03%

Minimum

-115.61%

Maximum

0%

Aileron Therapeutics, Inc. (ALRN) ROE by Quarter and Year

Discovering the peaks and valleys of Aileron Therapeutics, Inc. ROE, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Maximum Annual Increase = 0%

Maximum Annual ROE = 0%

Minimum Annual Increase = 0%

Minimum Annual ROE = -115.61%

Quarterly (TTM)
Annual
YearROEChange
2024-115.61%50.51%
2023-0.23%55.66%
2022-0.15%146.25%
2021-0.06%-65.74%
2020-0.17%-Infinity%
20190%0%
20180%0%
20170%0%
20160%0%

Aileron Therapeutics, Inc. (ALRN) Average ROE

How has ALRN ROE performed in the past?

The current ROE of Aileron Therapeutics, Inc. (ALRN) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

3-year avg

-38.66%

5-year avg

-23.24%

10-year avg

-11.62%

Aileron Therapeutics, Inc. (ALRN) ROE vs. Peers

How is ALRN’s ROE compared to its peers?

Aileron Therapeutics, Inc.’s ROE is greater than Lunai Bioworks Inc. (-385.07%), greater than Magenta Therapeutics, Inc. (-34.04%), greater than GreenLight Biosciences Holdings (-1847.24%), less than Pluristem Therapeutics Inc. (21.27%), greater than AlloVir, Inc. (-76.00%), greater than Spyre Therapeutics, Inc. (-31.18%), less than bluebird bio, Inc. (1.90%), greater than Kronos Bio, Inc. (-64.22%), greater than ERYTECH Pharma S.A. (-95.68%), greater than Lumos Pharma, Inc. (-197.75%),

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