The PE Ratio as of December 2025 (TTM) for Xilio Therapeutics, Inc. (XLO) is -1.21

According to Xilio Therapeutics, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -1.21. This represents a change of 49.66% compared to the average of -0.81 of the last 4 quarters.

Xilio Therapeutics, Inc. (XLO) Historical PE Ratio (quarterly & annually)

How has XLO PE Ratio performed in the past?

The mean historical PE Ratio of Xilio Therapeutics, Inc. over the last ten years is -44.94. The current -1.21 PE Ratio has changed 169.23% with respect to the historical average. Over the past ten years (40 quarters), XLO's PE Ratio was at its highest in in the September 2025 quarter at 0. The PE Ratio was at its lowest in in the September 2020 quarter at -7.20.

Xilio Therapeutics, Inc. (XLO) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Xilio Therapeutics, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Xilio Therapeutics, Inc. (XLO) Average PE Ratio

How has XLO PE Ratio performed in the past?

The current PE Ratio of Xilio Therapeutics, Inc. (XLO) is less than than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Xilio Therapeutics, Inc. (XLO) PE Ratio vs. Peers

How is XLO’s PE Ratio compared to its peers?

Xilio Therapeutics, Inc.’s PE Ratio is less than PDS Biotechnology Corporation (-1.20), greater than Actinium Pharmaceuticals, Inc. (-1.31), less than Tempest Therapeutics, Inc. (-0.30), greater than OnKure Therapeutics, Inc. (-5.35), greater than LAVA Therapeutics N.V. (-1.65), less than Kezar Life Sciences, Inc. (-0.65), greater than FibroGen, Inc. (-16.14), less than Skye Bioscience, Inc. (-1.13), greater than Tvardi Therapeutics, Inc. (-2.81), greater than Aligos Therapeutics, Inc. (-1.21),

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