Spruce Biosciences, Inc. - PE Ratio

The PE Ratio as of June 2026 (TTM) for Spruce Biosciences, Inc. (SPRB) is -1.46

According to Spruce Biosciences, Inc.’s latest financial reports and current stock price. The company's current PE Ratio is -1.46. This represents a change of 32.02% compared to the average of -1.11 of the last 4 quarters.

Spruce Biosciences, Inc. (SPRB) Historical PE Ratio (quarterly & annually)

How has SPRB PE Ratio performed in the past?

The mean historical PE Ratio of Spruce Biosciences, Inc. over the last ten years is -13.39. The current -1.46 PE Ratio has changed 990.08% with respect to the historical average. Over the past ten years (40 quarters), SPRB's PE Ratio was at its highest in in the September 2025 quarter at -0.15. The PE Ratio was at its lowest in in the September 2019 quarter at -77.41.

Spruce Biosciences, Inc. (SPRB) PE Ratio by Quarter and Year

Discovering the peaks and valleys of Spruce Biosciences, Inc. PE Ratio, unveiling quarterly and yearly fluctuations to gain insights into the company’s financial performance and market dynamics, offering valuable data for investors and analysts alike.

Spruce Biosciences, Inc. (SPRB) Average PE Ratio

How has SPRB PE Ratio performed in the past?

The current PE Ratio of Spruce Biosciences, Inc. (SPRB) is greater than its 3-year, greater than its 5-year, and greater than its 10-year historical averages

Spruce Biosciences, Inc. (SPRB) PE Ratio vs. Peers

How is SPRB’s PE Ratio compared to its peers?

Spruce Biosciences, Inc.’s PE Ratio is greater than NRx Pharmaceuticals, Inc. (-3.09), less than Werewolf Therapeutics, Inc. (-0.29), less than Outlook Therapeutics, Inc. (-1.16), less than IO Biotech, Inc. (-0.01), greater than Cue Biopharma, Inc. (-5.16), greater than OS Therapies Incorporated (-1.80), less than vTv Therapeutics Inc. (1.75K), greater than Equillium, Inc. (-8.11), greater than Coeptis Therapeutics, Inc. (-6.61),

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