Start with its own history
At 24.00×, NBIX is 78.7% below its 8-observation annual average. A lower multiple can reflect a lower price, higher earnings, or weaker growth expectations—not necessarily a bargain.
NASDAQ · NBIXBiotechnologyUpdated Nov 5, 2026
Neurocrine Biosciences, Inc. P/E ratio
Current valuation, historical context, and peer comparisons.
Current P/E ratio
24.00×
78.7% belowthe 8-observation annual average
Share price166.05
÷Earnings per share6.92
Price and EPS in quote currency. Calculation details
Investors are paying 24.00 for every 1 of reported earnings per share.
P/E over time
2016 – 2025
Annual P/ESelected-period average 112.52×
3-year average40.37×3 positive annual observations
5-year average56.99×5 positive annual observations
10-year average112.52×8 positive annual observations
Peer median · TTM12.03×4 peers with positive P/E
Historical P/E ratios
Annual period-end data · 25 observations
| Period end | P/E | Change |
|---|---|---|
| Dec 31, 2025 | 29.49× | -26.6% |
| Dec 31, 2024 | 40.15× | -22.0% |
| Dec 31, 2023 | 51.47× | -30.6% |
| Dec 31, 2022 | 74.19× | -17.3% |
| Dec 31, 2021 | 89.65× | +308.7% |
| Dec 31, 2020 | 21.93× | -91.8% |
| Dec 31, 2019 | 268.72× | -17.2% |
| Dec 31, 2018 | 324.59× | N/M |
View all 25 annual observations +
| Period end | P/E | Change |
|---|---|---|
| Dec 31, 2017 | N/M | N/M |
| Dec 31, 2016 | N/M | N/M |
| Dec 31, 2015 | N/M | N/M |
| Dec 31, 2014 | N/M | N/M |
| Dec 31, 2013 | N/M | N/M |
| Dec 31, 2012 | 97.65× | +681.2% |
| Dec 31, 2011 | 12.50× | N/M |
| Dec 31, 2010 | N/M | N/M |
| Dec 31, 2009 | N/M | N/M |
| Dec 31, 2008 | N/M | N/M |
| Dec 31, 2007 | N/M | N/M |
| Dec 31, 2006 | N/M | N/M |
| Dec 31, 2005 | N/M | N/M |
| Dec 31, 2004 | N/M | N/M |
| Dec 31, 2003 | N/M | N/M |
| Dec 31, 2002 | N/M | N/M |
| Dec 31, 2001 | N/M | N/M |
Change is relative to the preceding observation. N/M values are excluded from averages.
How NBIX compares
Company P/E vs. peer trailing-12-month ratios
| Company | P/E ratio |
|---|---|
 NBIX This stockNeurocrine Biosciences, Inc. | 24.00× |
 SUPNSupernus, Inc. | 7.71× |
 JAZZJazz Pharmaceuticals plc | 65.55× |
 VNDAVanda Pharmaceuticals Inc. | N/M |
 AXSMAxsome Therapeutics, Inc. | N/M |
 ACADAcadia Pharmaceuticals Inc. | 10.08× |
 RAPPRapport Therapeutics, Inc. Common Stock | N/M |
 HLBBFH. Lundbeck A/S | 13.98× |
 BHVNBiohaven Ltd. | N/M |
Peers are selected by the data provider. Business models and earnings definitions can differ.
Put the numbers in context
What does NBIX’s P/E tell you?
Compare like with like
The median of the 4 positive peer ratios above is 12.03×. Check growth, margins, debt, and earnings quality before interpreting the gap. A faster-growing business may justify a higher multiple.
Check what drives earnings
One-off gains can temporarily lower P/E; unusual charges can raise it. Reported earnings and forward estimates answer different questions. Pair this view with return on equity and liquidity for a fuller picture.
Keep your research connected
Take NBIX into your spreadsheet
Pull historical P/E into Excel or Google Sheets with Wisesheets. Build your own comparisons alongside the rest of your financial model.
Explore WisesheetsQuarterly P/E · latest quarterLQ selects the latest reported quarter. Requires the Wisesheets add-in. See available data
=WISE("NBIX", "PE Ratio", "LQ")Sources & calculation methodology
Current P/E
Share price 166.05 ÷ EPS 6.92 = 24.00×. Data is supplied by Financial Modeling Prep through Wisesheets. Quote feed updated Nov 5, 2026; this is not a real-time trading quote.
History & averages
Annual and quarterly P/E observations are provided separately from the current quote. Averages use the latest 3, 5, or 10 annual observations, excluding missing and nonpositive ratios. Pre-IPO observations are omitted. These are period-end observations, not daily averages.
Data definitions and limitations
The current quote feed does not specify the exact EPS filing-period end or whether EPS is basic or diluted. We do not label it as forward P/E. Peer ratios are explicitly trailing-12-month (TTM) values. Historical observations do not include independently verified price and EPS inputs. Sources may update on different schedules; rounded inputs can produce small calculation differences. Historical comparisons describe past pricing, not an estimate of fair value.
NBIX P/E ratio: common questions
The essentials behind the numbers.
Neurocrine Biosciences, Inc.'s current P/E is 24.00× based on the quote data last updated Nov 5, 2026. It represents the share price divided by reported earnings per share. Prices and earnings may refresh on different schedules.
Annual P/E uses earnings for a completed fiscal year. Trailing-12-month (TTM) P/E uses the latest four quarters, while forward P/E uses forecast earnings. These are not interchangeable. This page labels peer ratios as TTM and shows dated annual or quarterly historical observations; it does not show forward estimates.
N/M means not meaningful: the feed has no positive P/E for that observation. Negative or zero earnings should not be ranked as a low positive valuation multiple. N/M observations are excluded from the averages shown above.
Divide the share price by earnings per share (EPS). For example, a share price of 100 and EPS of 5 gives a P/E of 20×. This page uses the price and EPS supplied together in the quote when both are positive.
Price timestamps, EPS definitions, share classes, adjustments, and fiscal periods can differ. A forward P/E also uses forecast earnings rather than reported earnings. Compare the inputs and as-of dates before comparing two displayed ratios.
Not necessarily. The average describes previous market pricing, not fair value. Changes in earnings quality, growth expectations, debt, accounting, and business risk can justify a different multiple today.